8pj3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "8pj3" [edit=sysop:move=sysop])
Current revision (08:16, 14 August 2024) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8pj3 is ON HOLD
+
==Structure of human 48S translation initiation complex upon transfer of initiator tRNA to eIF5B (48S-3)==
-
 
+
<StructureSection load='8pj3' size='340' side='right'caption='[[8pj3]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
-
Authors:
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[8pj3]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PJ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PJ3 FirstGlance]. <br>
-
Description:
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pj3 OCA], [https://pdbe.org/8pj3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pj3 RCSB], [https://www.ebi.ac.uk/pdbsum/8pj3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pj3 ProSAT]</span></td></tr>
 +
</table>
 +
== Disease ==
 +
[https://www.uniprot.org/uniprot/RS19_HUMAN RS19_HUMAN] Blackfan-Diamond disease. Diamond-Blackfan anemia 1 (DBA1) [MIM:[https://omim.org/entry/105650 105650]: A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of developing leukemia. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:17517689</ref> <ref>PMID:12586610</ref> <ref>PMID:9988267</ref> <ref>PMID:10590074</ref> <ref>PMID:11112378</ref> <ref>PMID:12750732</ref> <ref>PMID:15384984</ref> [REFERENCE:18]
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/RS19_HUMAN RS19_HUMAN] Required for pre-rRNA processing and maturation of 40S ribosomal subunits.<ref>PMID:16990592</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Fischer N]]
 +
[[Category: Liedtke D]]
 +
[[Category: Peng BZ]]
 +
[[Category: Petrychenko V]]
 +
[[Category: Rodnina MV]]
 +
[[Category: Yi S-H]]

Current revision

Structure of human 48S translation initiation complex upon transfer of initiator tRNA to eIF5B (48S-3)

PDB ID 8pj3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/8pj3"
Personal tools