8t1v
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of orphan G protein-coupled receptor 6 with bound inverse agonist 3h== | |
| - | + | <StructureSection load='8t1v' size='340' side='right'caption='[[8t1v]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8t1v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8T1V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8T1V FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XY8:3-[4-[[2,4-bis(fluoranyl)phenyl]methyl]piperazin-1-yl]-7-methyl-~{N}-propan-2-yl-pyrido[3,4-b]pyrazin-2-amine'>XY8</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8t1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8t1v OCA], [https://pdbe.org/8t1v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8t1v RCSB], [https://www.ebi.ac.uk/pdbsum/8t1v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8t1v ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/GPR6_HUMAN GPR6_HUMAN] Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Barekatain M]] | ||
| + | [[Category: Beresford M]] | ||
| + | [[Category: Bliesath J]] | ||
| + | [[Category: Brice N]] | ||
| + | [[Category: Carlson L]] | ||
| + | [[Category: Cherezov V]] | ||
| + | [[Category: Han GW]] | ||
| + | [[Category: Hua T]] | ||
| + | [[Category: Johansson L]] | ||
| + | [[Category: Katritch V]] | ||
| + | [[Category: Lam JH]] | ||
| + | [[Category: Liu Z]] | ||
| + | [[Category: Lutomski C]] | ||
| + | [[Category: Monenschein H]] | ||
| + | [[Category: Murphy S]] | ||
| + | [[Category: Popov P]] | ||
| + | [[Category: Robinson CV]] | ||
| + | [[Category: Russo J]] | ||
| + | [[Category: Sadybekov AV]] | ||
| + | [[Category: Saikatendu KS]] | ||
| + | [[Category: Schiffer HH]] | ||
| + | [[Category: Sun H]] | ||
Current revision
Crystal structure of orphan G protein-coupled receptor 6 with bound inverse agonist 3h
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Categories: Escherichia coli | Homo sapiens | Large Structures | Barekatain M | Beresford M | Bliesath J | Brice N | Carlson L | Cherezov V | Han GW | Hua T | Johansson L | Katritch V | Lam JH | Liu Z | Lutomski C | Monenschein H | Murphy S | Popov P | Robinson CV | Russo J | Sadybekov AV | Saikatendu KS | Schiffer HH | Sun H
