This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8tar
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8tar is ON HOLD Authors: Description: Category: Unreleased Structures) |
|||
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==APC/C-CDH1-UBE2C-Ubiquitin-CyclinB-NTD== | |
| - | + | <StructureSection load='8tar' size='340' side='right'caption='[[8tar]], [[Resolution|resolution]] 4.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8tar]] is a 13 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TAR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TAR FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tar FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tar OCA], [https://pdbe.org/8tar PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tar RCSB], [https://www.ebi.ac.uk/pdbsum/8tar PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tar ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/APC1_HUMAN APC1_HUMAN] Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.<ref>PMID:18485873</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Amann SJ]] | ||
| + | [[Category: Bodrug T]] | ||
| + | [[Category: Bolhuis DL]] | ||
| + | [[Category: Bonacci T]] | ||
| + | [[Category: Brown NG]] | ||
| + | [[Category: Cui L]] | ||
| + | [[Category: Emanuele MJ]] | ||
| + | [[Category: Grishkovskaya I]] | ||
| + | [[Category: Hahn KM]] | ||
| + | [[Category: Harrison JS]] | ||
| + | [[Category: Haselbach D]] | ||
| + | [[Category: Liu B]] | ||
| + | [[Category: Martinez-Chacin RC]] | ||
| + | [[Category: Paulakonis E]] | ||
| + | [[Category: Pinkin N]] | ||
| + | [[Category: Roscow O]] | ||
| + | [[Category: Steimel JP]] | ||
| + | [[Category: Welsh KA]] | ||
| + | [[Category: Xu P]] | ||
| + | [[Category: Zhang W]] | ||
| + | [[Category: Zhong E]] | ||
Current revision
APC/C-CDH1-UBE2C-Ubiquitin-CyclinB-NTD
| |||||||||||
Categories: Homo sapiens | Large Structures | Amann SJ | Bodrug T | Bolhuis DL | Bonacci T | Brown NG | Cui L | Emanuele MJ | Grishkovskaya I | Hahn KM | Harrison JS | Haselbach D | Liu B | Martinez-Chacin RC | Paulakonis E | Pinkin N | Roscow O | Steimel JP | Welsh KA | Xu P | Zhang W | Zhong E
