Lidocaine

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<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='97/976786/Cv/1'>
<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='97/976786/Cv/1'>
Lidocaine, also known as lignocaine and sold under the brand name Xylocaine among others, is a local anesthetic of the amino amide type. It is also used to treat ventricular tachycardia.<ref name="a7">"Lidocaine Hydrochloride (Antiarrhythmic)". The American Society of Health-System Pharmacists. Archived from the original on 2015-08-10. Retrieved Aug 26, 2015.</ref><ref name="a8">"Lidocaine Hydrochloride (Local)". The American Society of Health-System Pharmacists. Archived from the original on 2015-09-06. Retrieved Aug 26, 2015.</ref> When used for local anaesthesia or in nerve blocks, lidocaine typically begins working within several minutes and lasts for half an hour to three hours.<ref name="a8">"Lidocaine Hydrochloride (Local)". The American Society of Health-System Pharmacists. Archived from the original on 2015-09-06. Retrieved Aug 26, 2015.</ref><ref name="a9">Nolan JP, Baskett PJ (1997). "Analgesia and anaesthesia". In David Skinner, Andrew Swain, Rodney Peyton, Colin Robertson (eds.). Cambridge Textbook of Accident and Emergency Medicine. Project co-ordinator, Fiona Whinster. Cambridge, UK: Cambridge University Press. p. 194. ISBN 9780521433792. Archived from the original on 2017-09-08.</ref> Lidocaine mixtures may also be applied directly to the skin or mucous membranes to numb the area.<ref name="a8">"Lidocaine Hydrochloride (Local)". The American Society of Health-System Pharmacists. Archived from the original on 2015-09-06. Retrieved Aug 26, 2015.</ref> It is often used mixed with a small amount of adrenaline (epinephrine) to prolong its local effects and to decrease bleeding.<ref name="a8">"Lidocaine Hydrochloride (Local)". The American Society of Health-System Pharmacists. Archived from the original on 2015-09-06. Retrieved Aug 26, 2015.</ref> See also [https://en.wikipedia.org/wiki/Lidocaine].
Lidocaine, also known as lignocaine and sold under the brand name Xylocaine among others, is a local anesthetic of the amino amide type. It is also used to treat ventricular tachycardia.<ref name="a7">"Lidocaine Hydrochloride (Antiarrhythmic)". The American Society of Health-System Pharmacists. Archived from the original on 2015-08-10. Retrieved Aug 26, 2015.</ref><ref name="a8">"Lidocaine Hydrochloride (Local)". The American Society of Health-System Pharmacists. Archived from the original on 2015-09-06. Retrieved Aug 26, 2015.</ref> When used for local anaesthesia or in nerve blocks, lidocaine typically begins working within several minutes and lasts for half an hour to three hours.<ref name="a8">"Lidocaine Hydrochloride (Local)". The American Society of Health-System Pharmacists. Archived from the original on 2015-09-06. Retrieved Aug 26, 2015.</ref><ref name="a9">Nolan JP, Baskett PJ (1997). "Analgesia and anaesthesia". In David Skinner, Andrew Swain, Rodney Peyton, Colin Robertson (eds.). Cambridge Textbook of Accident and Emergency Medicine. Project co-ordinator, Fiona Whinster. Cambridge, UK: Cambridge University Press. p. 194. ISBN 9780521433792. Archived from the original on 2017-09-08.</ref> Lidocaine mixtures may also be applied directly to the skin or mucous membranes to numb the area.<ref name="a8">"Lidocaine Hydrochloride (Local)". The American Society of Health-System Pharmacists. Archived from the original on 2015-09-06. Retrieved Aug 26, 2015.</ref> It is often used mixed with a small amount of adrenaline (epinephrine) to prolong its local effects and to decrease bleeding.<ref name="a8">"Lidocaine Hydrochloride (Local)". The American Society of Health-System Pharmacists. Archived from the original on 2015-09-06. Retrieved Aug 26, 2015.</ref> See also [https://en.wikipedia.org/wiki/Lidocaine].
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Lidocaine alters signal conduction in neurons by prolonging the inactivation of the fast voltage-gated Na+ channels in the neuronal cell membrane responsible for action potential propagation.
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== References ==
== References ==
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References

  1. "Lidocaine Hydrochloride (Antiarrhythmic)". The American Society of Health-System Pharmacists. Archived from the original on 2015-08-10. Retrieved Aug 26, 2015.
  2. 2.0 2.1 2.2 2.3 "Lidocaine Hydrochloride (Local)". The American Society of Health-System Pharmacists. Archived from the original on 2015-09-06. Retrieved Aug 26, 2015.
  3. Nolan JP, Baskett PJ (1997). "Analgesia and anaesthesia". In David Skinner, Andrew Swain, Rodney Peyton, Colin Robertson (eds.). Cambridge Textbook of Accident and Emergency Medicine. Project co-ordinator, Fiona Whinster. Cambridge, UK: Cambridge University Press. p. 194. ISBN 9780521433792. Archived from the original on 2017-09-08.

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