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8k2x
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8k2x is ON HOLD Authors: Jiao, H.Z., Hu, H.L. Description: CXCR3-DNGi complex activated by CXCL10 Category: Unreleased Structures [[Category: J...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==CXCR3-DNGi complex activated by CXCL10== | |
| - | + | <StructureSection load='8k2x' size='340' side='right'caption='[[8k2x]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8k2x]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oplophorus_gracilirostris Oplophorus gracilirostris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8K2X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8K2X FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8k2x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8k2x OCA], [https://pdbe.org/8k2x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8k2x RCSB], [https://www.ebi.ac.uk/pdbsum/8k2x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8k2x ProSAT]</span></td></tr> |
| - | [[Category: Hu | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Oplophorus gracilirostris]] | ||
| + | [[Category: Hu HL]] | ||
| + | [[Category: Jiao HZ]] | ||
Current revision
CXCR3-DNGi complex activated by CXCL10
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