Ion channels 3D structures

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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
-
* Potassium channel See: [[Potassium_Channel#Additional_Structures_of_Potassium_Channels|Potassium Channels]]
+
*Calcium channel
-
* Calcium channel
+
**[[2d46]] – hVDCC beta 4a – NMR – human
-
 
+
-
**[[2d46]] – hVDCC β 4a – human - NMR<br />
+
**[[6nq0]], [[6nq1]], [[6nq2]] – hTpc2 – Cryo EM <br />
**[[6nq0]], [[6nq1]], [[6nq2]] – hTpc2 – Cryo EM <br />
**[[8if4]] – hCav alpha-2+delta-1 – Cryo EM <br />
**[[8if4]] – hCav alpha-2+delta-1 – Cryo EM <br />
**[[8if3]] – hCav alpha-2+delta-1 + drug – Cryo EM <br />
**[[8if3]] – hCav alpha-2+delta-1 + drug – Cryo EM <br />
-
**[[2f3y]], [[2f3z]], [[2be6]] – hCav1.2 α 1C subunit+calmodulin <br />
+
**[[2be6]], [[2f3y]], [[2f3z]] – hCav1.2 alpha 1C subunit+calmodulin
-
**[[3oxq]] - hCav2.1 α 1C subunit IQ domain+hCalmodulin<br />
+
**[[3oxq]] - hCav2.1 alpha 1C subunit IQ domain+hCalmodulin
-
**[[2vay]], [[3oxq]] - hCav1.1 α 1S subunit IQ domain+hCalmodulin<br />
+
**[[2vay]], [[3oxq]] – hCav1.1 alpha 1S subunit IQ domain+hCalmodulin
**[[8eoi]] – hCav1.2 in EMC chaperone – Cryo EM <br />
**[[8eoi]] – hCav1.2 in EMC chaperone – Cryo EM <br />
**[[8fd7]] – hCav1.2 + drug – Cryo EM <br />
**[[8fd7]] – hCav1.2 + drug – Cryo EM <br />
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**[[6jpa]], [[6jpb]] – rCav1.1 + blocker – Cryo EM<br />
**[[6jpa]], [[6jpb]] – rCav1.1 + blocker – Cryo EM<br />
**[[8e56]], [[8e57]], [[8e58]] – rCav1.1 + drug – Cryo EM<br />
**[[8e56]], [[8e57]], [[8e58]] – rCav1.1 + drug – Cryo EM<br />
-
**[[3bxx]] – rCav2.1 α 1A subunit+calmodulin - rabbit<br />
+
**[[3bxx]] – rCav2.1 alpha 1A subunit+calmodulin
-
**[[3bxl]] - rCav2.3 α 1E subunit+calmodulin<br />
+
**[[3bxl]] - rCav2.3 alpha 1E subunit+calmodulin
-
**[[1t0h]] – rVDCC β 2A subunit <br />
+
**[[1t0h]] – rVDCC beta 2A subunit
-
**[[1t0j]] – rVDCC β 2A+α 1C <br />
+
**[[1t0j]] – rVDCC beta 2A+ 1C
-
**[[1vyt]] - rVDCC β 3+α 1C <br />
+
**[[1vyt]] - rVDCC beta 3+ 1C
-
**[[1vyu]] – rVDCC β 3<br />
+
**[[1vyu]] – rVDCC beta 3
-
**[[1vyv]] - rVDCC β 4<br />
+
**[[1vyv]] - rVDCC beta 4
-
**[[6hw2]] - rVDCC β 4 + chromobox protein<br />
+
**[[6hw2]] - rVDCC beta 4 + chromobox protein<br />
-
**[[1t3l]] - rVDCC β 2+α 1S <br />
+
**[[1t3l]] - rVDCC beta 2+ 1S
-
**[[1t3s]] - rVDCC β 2<br />
+
**[[1t3s]] - rVDCC beta 2
-
**[[3dve]], [[3dvj]], [[3dvk]], [[3dvm]], [[3g43]] - rCav2.2 α 1B subunit+hCalmodulin<br />
+
**[[3dve]], [[3dvj]], [[3dvk]], [[3dvm]], [[3g43]] - rCav2.2 alpha 1B subunit+hCalmodulin
-
**[[4dex]] - rCav2.2 α 1B + β 2 subunits<br />
+
**[[4dex]] - rCav2.2 alpha 1B + beta 2 subunits<br />
-
**[[4dey]] - rCav2.2 α 1C + β 2 subunits<br />
+
**[[4dey]] - rCav2.2 alpha 1C + beta 2 subunits<br />
-
**[[6byo]] – rCav1.1 α 1S <br />
+
**[[6byo]] – rCav1.1 alpha 1S <br />
-
**[[5gjw]] – rCav1.1 α 2/δ 1 + α 1S + β 1 – Cryo EM<br />
+
**[[5gjw]] – rCav1.1 alpha 2/d 1 + alpha 1S + beta 1 – Cryo EM<br />
-
**[[5gjv]], [[3jbr]] – rCav1.1 α 2/δ 1 + α 1S + β 1 + γ 1 – Cryo EM<br />
+
**[[3jbr]], [[5gjv]] – rCav1.1 alpha 2/d 1 + alpha 1S + beta 1 + gamma 1 – Cryo EM<br />
-
**[[5v2q]], [[5v2p]] - raCav1.2 alpha 1C + beta 2 - rat<br />
+
**[[5v2p]], [[5v2q]] - raCav1.2 alpha 1C + beta 2 - rat<br />
-
**[[7qhh]] - raVDCC gamma 8 + glutamate receptor 1 – Cryo EM<br />
+
**[[7qhh]] - raVDCC g 8 + glutamate receptor 1 – Cryo EM<br />
-
**[[5vov]], [[5vou]], [[5vot]], [[5kk2]] - raVDCC γ 2 + glutamate receptor 2 – Cryo EM<br />
+
**[[5kk2]], [[5vov]], [[5vou]], [[5vot]] - raVDCC gamma 2 + glutamate receptor 2 – Cryo EM<br />
-
**[[6njl]], [[6njm]], [[6njn]] - raVDCC γ 2 + glutamate receptor 1 + glutamate receptor 2 + a’/c’ auxiliary protein + antibody – Cryo EM<br />
+
**[[6njl]], [[6njm]], [[6njn]] - raVDCC gamma 2 + glutamate receptor 1 + glutamate receptor 2 + a’/c’ auxiliary protein + antibody – Cryo EM<br />
-
**[[6qkc]], [[6qkz]], [[7ocd]] - raVDCC γ 8 + glutamate receptor 1 + glutamate receptor 2 – Cryo EM<br />
+
**[[6qkc]], [[6qkz]], [[7ocd]] - raVDCC gamma 8 + glutamate receptor 1 + glutamate receptor 2 – Cryo EM<br />
-
**[[7oca]], [[7oce]], [[7ocf]] - raVDCC γ 8 + glutamate receptor 1 + glutamate receptor 2 + CNIH-2 – Cryo EM<br />
+
**[[7oca]], [[7oce]], [[7ocf]] - raVDCC gamma 8 + glutamate receptor 1 + glutamate receptor 2 + CNIH-2 – Cryo EM<br />
-
**[[8e0e]] – raCav L-type 2 + nanobody<br />
+
**[[8e0e]] – raCav L-type beta 2 + nanobody<br />
-
**[[6c9a]], [[6c96]] – mTpc1 - mouse <br />
+
**[[6c96]], [[6c9a]] – mTpc1 - mouse – Cryo EM <br />
-
**[[6c96]], [[6c9a]] – mTpc1 – Cryo EM <br />
+
**[[4zw2]] – mVDCC alpha 1S peptide + beta 1 <br />
-
**[[4zw2]] – mVDCC α 1S peptide + β 1 <br />
+
**[[7lep]] - mVDCC g 8 + glutamate receptor 2 + AMPAR subunits + CNIH-2 – Cryo EM<br />
-
**[[7lep]] - mVDCC γ 8 + glutamate receptor 2 + AMPAR subunits + CNIH-2 – Cryo EM<br />
+
**[[8dam]] – mCav L-type beta 1 + nanobody<br />
-
**[[8dam]] – mCav L-type 1 + nanobody<br />
+
**[[5dqq]], [[5e1j]], [[5tua]], [[7fhk]], [[7fhl]] – AtTpc1 – Arabidopsis thaliana <br />
-
**[[5tua]], [[5e1j]], [[5dqq]], [[7fhk]], [[7fhl]] – AtTpc1 – ''Arabidopsis thaliana'' <br />
+
**[[6cx0]] – AtTpc1 (mutant) <br />
**[[6cx0]] – AtTpc1 (mutant) <br />
**[[6e1m]], [[6e1n]], [[6e1p]], [[7fhn]], [[7fho]], [[7tbg]], [[7tdd]], [[7tde]], [[7tdf]] – AtTpc1 (mutant) – Cryo EM <br />
**[[6e1m]], [[6e1n]], [[6e1p]], [[7fhn]], [[7fho]], [[7tbg]], [[7tdd]], [[7tde]], [[7tdf]] – AtTpc1 (mutant) – Cryo EM <br />
**[[6e1k]] – AtTpc1 + antibody – Cryo EM <br />
**[[6e1k]] – AtTpc1 + antibody – Cryo EM <br />
-
**[[6mgv]], [[6mgw]], [[6ijz]] – AtOsca1.2 – Cryo EM <br />
+
**[[6ijz]], [[6mgv]], [[6mgw]] – AtOsca1.2 – Cryo EM <br />
-
**[[4mtf]], [[4mtg]], [[4mto]] – AbCaV + Ca – ''Arcobacter butzleri''<br />
+
**[[4mtf]], [[4mtg]], [[4mto]] – AbCaV + Ca – Arcobacter butzleri<br />
-
 
+
-
*See also [[Ryanodine receptor]]
+
*Sodium channel; Domains – extracellular 30-157
*Sodium channel; Domains – extracellular 30-157
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**[[6uz3]] – raNaV 5 - Cryo EM<br />
**[[6uz3]] – raNaV 5 - Cryo EM<br />
**[[1qg9]] – raNaCh IIA second repeat – NMR<br />
**[[1qg9]] – raNaCh IIA second repeat – NMR<br />
-
**[[5ayq]], [[5xax]], [[5xaw]] - mNaV 4 residues 30-160 <br />
+
**[[5ayq]], [[5xaw]], [[5xax]] - mNaV 4 residues 30-160 <br />
**[[5xsy]] – eeNaV 1.4 + beta 1 – electric eel - Cryo EM <br />
**[[5xsy]] – eeNaV 1.4 + beta 1 – electric eel - Cryo EM <br />
**[[5x0m]] – coNaCh - cockroach <br />
**[[5x0m]] – coNaCh - cockroach <br />
-
**[[4bgn]] – NaCh –'' Caldalkalibacillus thermarum'' – Cryo EM<br />
+
**[[4bgn]] – NaCh – Caldalkalibacillus thermarum – Cryo EM<br />
-
**[[4lto]], [[4ltp]], [[4ltq]], [[5hk7]] – AeNaCh pore + cytoplasmic domains – ''Alkalilimnicola ehrlichii'' <br />
+
**[[4lto]], [[4ltp]], [[4ltq]], [[5hk7]] – AeNaCh pore + cytoplasmic domains – Alkalilimnicola ehrlichii <br />
-
**[[4ltr]], [[5hkd]], [[5hk6]], [[5kj8]] – AeNaCh pore + cytoplasmic domains (mutant) <br />
+
**[[4ltr]], [[5hk6]], [[5hkd]], [[5kj8]] – AeNaCh pore + cytoplasmic domains (mutant) <br />
**[[5iwn]], [[7pgh]] – AeNaCh pore domain<br />
**[[5iwn]], [[7pgh]] – AeNaCh pore domain<br />
**[[7x5v]] – NaV – Emiliania huxleyi - Cryo EM<br />
**[[7x5v]] – NaV – Emiliania huxleyi - Cryo EM<br />
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**[[6wth]] – hENaC alpha+beta+gamma subunits + antibody – Cryo EM<br />
**[[6wth]] – hENaC alpha+beta+gamma subunits + antibody – Cryo EM<br />
**[[6lqa]] – hNaV 1.5 + quinidine - Cryo EM<br />
**[[6lqa]] – hNaV 1.5 + quinidine - Cryo EM<br />
-
**[[4ovn]], [[5dbr]], [[4djc]], [[6mud]] – hNaV 1.5 C terminal + calmodulin <br />
+
**[[4djc]], [[4ovn]], [[5dbr]], [[6mud]] – hNaV 1.5 C terminal + calmodulin <br />
**[[4dck]], [[4jq0]] – hNaV 1.5 C terminal + calmodulin + fibroblast growth factor <br />
**[[4dck]], [[4jq0]] – hNaV 1.5 C terminal + calmodulin + fibroblast growth factor <br />
**[[4jpz]] – hNaV 1.2 C terminal + calmodulin + fibroblast growth factor 13<br />
**[[4jpz]] – hNaV 1.2 C terminal + calmodulin + fibroblast growth factor 13<br />
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*Sodium channel, pre-activated. NavAb
*Sodium channel, pre-activated. NavAb
-
**[[4ekw]], [[4mw8]], [[5vb2]], [[5yua]], [[6mwa]] - AbNaVab – ''Arcobacter butzleri''<br />
+
**[[4ekw]], [[4mw8]], [[5vb2]], [[5yua]], [[6mwa]] - AbNaVab<br />
**[[3rvy]], [[3rvz]], [[3rw0]], [[5yuc]], [[5yub]], [[6c1e]], [[6c1m]], [[6mwb]], [[6mwd]], [[6mwg]], [[6p6w]], [[6p6x]], [[6p6y]] - AbNaVab (mutant) <br />
**[[3rvy]], [[3rvz]], [[3rw0]], [[5yuc]], [[5yub]], [[6c1e]], [[6c1m]], [[6mwb]], [[6mwd]], [[6mwg]], [[6p6w]], [[6p6x]], [[6p6y]] - AbNaVab (mutant) <br />
**[[6mvv]], [[6mvy]] - AbNaVab (mutant) + lidocaine <br />
**[[6mvv]], [[6mvy]] - AbNaVab (mutant) + lidocaine <br />
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*Sodium channel, activated. NavMs
*Sodium channel, activated. NavMs
-
**[[3zjz]], [[4cbc]], [[4f4l]], [[4x89]], [[4x8a]], [[5bzb]], [[5hvx]] – MmNavMs – ''Magnetococcus marinus'' <br />
+
**[[3zjz]], [[4cbc]], [[4f4l]], [[4x89]], [[4x8a]], [[5bzb]], [[5hvx]] – MmNavMs – Magnetococcus marinus <br />
**[[4x88]], [[5hvd]], [[6sx5]], [[6sx7]], [[6yz2]] – MmNavMs (mutant) <br />
**[[4x88]], [[5hvd]], [[6sx5]], [[6sx7]], [[6yz2]] – MmNavMs (mutant) <br />
**[[4osx]], [[4p2z]], [[4p30]], [[4p9o]], [[4p9p]], [[4pa3]], [[4pa4]], [[4pa6]], [[4pa7]], [[4pa9]] – MmNavMs + blocker<br />
**[[4osx]], [[4p2z]], [[4p30]], [[4p9o]], [[4p9p]], [[4pa3]], [[4pa4]], [[4pa6]], [[4pa7]], [[4pa9]] – MmNavMs + blocker<br />
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**[[6yz0]] – MmNavMs (mutant) + cannabidiol<br />
**[[6yz0]] – MmNavMs (mutant) + cannabidiol<br />
-
* NH4+ channel
+
*Potassium channel see [[Potassium Channel]]
-
**[[2nmr]], [[2nop]], [[2now]], [[2npc]], [[2npd]], [[2npe]], [[2npj]], [[2npg]], [[2npk]], [[1u77]], [[1u7c]], [[1u7g]], [[1xqe]], [[1xqf]], [[3c1g]] – EcAmCh – ''Escherichia coli''<br />
+
*NH4+ channel
 +
 
 +
**[[1u77]], [[1u7c]], [[1u7g]], [[1xqe]], [[1xqf]], [[2nmr]], [[2nop]], [[2now]], [[2npc]], [[2npd]], [[2npe]], [[2npg]], [[2npj]], [[2npk]], [[1u77]], [[3c1g]] – EcAmCh – Escherichia coli
**[[3c1h]], [[3c1i]], [[3c1j]] – EcAmCh (mutant)<br />
**[[3c1h]], [[3c1i]], [[3c1j]] – EcAmCh (mutant)<br />
**[[4nh2]] – EcAmCh + phosphatidylglycerol<br />
**[[4nh2]] – EcAmCh + phosphatidylglycerol<br />
**[[2ns1]], [[2nuu]] – EcAmCh + nitrogen regulatory protein<br />
**[[2ns1]], [[2nuu]] – EcAmCh + nitrogen regulatory protein<br />
-
**[[2b2h]], [[2b2i]], [[2b2j]], [[2b2f]] – AmCh – ''Archaeglobus fulgidus''<br />
+
**[[2b2f]], [[2b2h]], [[2b2i]], [[2b2j]] – AmCh – Archaeglobus fulgidus
-
**[[3b9w]], [[3b9y]], [[3bhs]] – AmCh – ''Nitrosomonas europaea''
+
**[[3b9w]], [[3b9y]], [[3bhs]] – AmCh – Nitrosomonas europaea
-
* MscL and MscS
+
*MscL and MscS
-
**[[3hzq]] – MscL – ''Staphylococcus aureus''<br />
+
**[[3hzq]] – MscL – Staphylococcus aureus
-
**[[2oar]], [[6ctd]] – MtMscL – ''Mycobacterium tuberculosis''<br />
+
**[[2oar]], [[6ctd]] – MscL – Mycobacterium tuberculosis
-
**[[4lku]] – EcMscL C terminal<br />
+
**[[2oau]], [[2vv5]], [[4hwa]] – EcMscS
-
**[[4y7k]], [[4y7j]] – MscL – ''Methanosarcina acetivorans''<br />
+
**[[6pwn]], [[6pwo]], [[6pwp]], [[6rld]], [[6uzh]], [[6vyk]], [[6vyl]], [[6vym]], [[7onj]], [[7onl]], [[7oo0]], [[7oo6]], [[7oo8]], [[7ooa]], [[7raz]], [[8ddj]] – EcMscS – Cryo EM<br />
-
**[[2oau]], [[2vv5]], [[4hwa]] - EcMscS<br />
+
-
**[[6pwn]], [[6pwo]], [[6pwp]], [[6rld]], [[6uzh]], [[6vyk]], [[6vyl]], [[6vym]], [[7onj]], [[7onl]], [[7oo0]], [[7oo6]], [[7oo8]], [[7ooa]] – EcMscS – Cryo EM<br />
+
**[[4age]], [[4agf]], [[5aji]] – EcMscS (mutant)<br />
**[[4age]], [[4agf]], [[5aji]] – EcMscS (mutant)<br />
-
**[[3t9n]], [[3udc]] – MscS – ''Thermoanaerobacter tengcongensis''<br />
+
**[[4lku]] – EcMscL C terminal<br />
-
**[[4hw9]] – MscS – ''Helicobacter pylori''<br />
+
**[[4y7j]], [[4y7k]] – MscL – Methanosarcina acetivorans<br />
 +
**[[3t9n]], [[3udc]] – MscS – Thermoanaerobacter tengcongensis<br />
 +
**[[4hw9]] – MscS – Helicobacter pylori<br />
**[[6lyp]], [[6vxm]], [[6vxn]], [[6vxp]] – AtMsc-like (mutant) – Cryo EM<br />
**[[6lyp]], [[6vxm]], [[6vxn]], [[6vxp]] – AtMsc-like (mutant) – Cryo EM<br />
 +
**[[8jwe]], [[8tdj]], [[8tdl]] – AtMs protein 10 – Cryo EM<br />
 +
**[[8tdk]], [[8tdm]] – AtMs protein 10 (mutant) – Cryo EM<br />
 +
**[[7dlu]] – MscS (mutant) – Pseudomonas aeruginosa – Cryo EM<br />
 +
**[[9bgq]], [[9bgs]] – TcMscS – Trypanosoma cruzi – Cryo EM<br />
 +
**[[9bgt]], [[9bgu]] – TcMscS (mutant) – Cryo EM<br />
-
* Chloride channel or H(+)/Cl(-) exchange transporter ClcA or human proton-activated chloride channel PAC
+
*Chloride channel or H(+)/Cl(-) exchange transporter ClcA or human proton-activated chloride channel PAC or CLIC
-
**[[1rk4]], [[3swl]] - hClCh protein 1<br />
+
**[[1rk4]], [[3swl]], [[7f8r]] - hClCh protein 1
-
**[[6qvu]], [[6qvd]], [[6qvc]], [[6qvb]], [[6qv6]] - hClCh protein 1 – Cryo EM<br />
+
**[[6qv6]], [[6qvb]], [[6qvc]], [[6qvd]], [[6qvu]] - hClCh protein 1 – Cryo EM<br />
-
**[[3o3t]], [[3p8w]], [[3p90]], [[1k0o]], [[3qr6]], [[3tgz]], [[1k0m]], [[3uvh]], [[4iqa]], [[4jzq]], [[4k0g]], [[4k0n]] - hClCh protein 1 (mutant)<br />
+
**[[1k0m]], [[1k0o]], [[3o3t]], [[3p8w]], [[3p90]], [[3qr6]], [[3tgz]], [[3uvh]], [[4iqa]], [[4jzq]], [[4k0g]], [[4k0n]] - hClCh protein 1 (mutant)
**[[6coz]] - hClCh protein 1 C terminal<br />
**[[6coz]] - hClCh protein 1 C terminal<br />
**[[6coy]] - hClCh protein 1 transmembrane domain<br />
**[[6coy]] - hClCh protein 1 transmembrane domain<br />
 +
**[[7fbq]] - hClCh protein 1 + pyrimidine derivative<br />
**[[1k0n]] - hClCh protein 1 (mutant) + glutathione<br />
**[[1k0n]] - hClCh protein 1 (mutant) + glutathione<br />
-
**[[2per]], [[2r4v]], [[2r5g]] - hClCh protein 2<br />
+
**[[2per]], [[2r4v]], [[2r5g]] - hClCh protein 2
-
**[[3kjy]], [[3fy7]] - hClCh protein 3 residues 1-230<br />
+
**[[7xf5]], [[7xja]] - hClCh protein 2 – Cryo EM<br />
-
**[[2ahe]], [[2d2z]] – hClCh protein 4<br />
+
**[[3fy7]], [[3kjy]] - hClCh protein 3 residues 1-230
 +
**[[2ahe]], [[2d2z]] – hClCh protein 4
**[[2pfi]] - hClCh KA<br />
**[[2pfi]] - hClCh KA<br />
**[[6y2h]] - hClCh protein 5<br />
**[[6y2h]] - hClCh protein 5<br />
Line 181: Line 185:
**[[7cq7]] - hClCh protein 7 + OSTM1 + ADP – Cryo EM<br />
**[[7cq7]] - hClCh protein 7 + OSTM1 + ADP – Cryo EM<br />
**[[7cq5]], [[7jm7]] - hClCh protein 7 + OSTM1 + ATP – Cryo EM<br />
**[[7cq5]], [[7jm7]] - hClCh protein 7 + OSTM1 + ATP – Cryo EM<br />
-
**[[7jna]], [[7jnc]] - hClCh PAC – Cryo EM<br />
+
**[[7jna]], [[7jnc]], [[7sqf]], [[7sqg]], [[7sqh]], [[8eq4]], [[8fbl]] - hClCh PAC – Cryo EM<br />
-
**[[5tr1]], [[5tqq]] - bCIC (mutant) + antibody – bovine - Cryo EM<br />
+
**[[5tqq]], [[5tr1]] - bCIC (mutant) + antibody – bovine - Cryo EM<br />
**[[6erz]], [[6ery]] - mClCh protein 6<br />
**[[6erz]], [[6ery]] - mClCh protein 6<br />
**[[7jm6]] - cClCh protein 7 + ATP – chicken - Cryo EM<br />
**[[7jm6]] - cClCh protein 7 + ATP – chicken - Cryo EM<br />
Line 188: Line 192:
**[[1ots]], [[6k5f]] - EcERIC + antibody<br />
**[[1ots]], [[6k5f]] - EcERIC + antibody<br />
**[[1ott]], [[1otu]], [[6ad7]], [[6ad8]], [[6ada]], [[6adb]], [[6adc]], [[6k5a]], [[6k5d]], [[7cvs]], [[7cvt]] - EcERIC (mutant) + antibody<br />
**[[1ott]], [[1otu]], [[6ad7]], [[6ad8]], [[6ada]], [[6adb]], [[6adc]], [[6k5a]], [[6k5d]], [[7cvs]], [[7cvt]] - EcERIC (mutant) + antibody<br />
-
**[[2d4z]] - TmClCh - ''Torpedo marmorata''<br />
+
**[[2d4z]] - TmClCh -Torpedo marmorata<br />
-
**[[2yv9]] - CeClCh EXC-4 – ''Caenorhabditis elegans''<br />
+
**[[2yv9]] - CeClCh EXC-4 – Caenorhabditis elegans<br />
**[[3rif]] - CeClCh + antibody + Glu + Ivermectin<br />
**[[3rif]] - CeClCh + antibody + Glu + Ivermectin<br />
-
**[[7ji3]] - CICh – ''Takifugu bimaculatus'' - Cryo EM<br />
+
**[[7ji3]] - CIC – Takifugu bimaculatus - Cryo EM<br />
-
**[[5y7i]] - ClCh – ''Oreochromis mossabicus''<br />
+
**[[5y7i]] - ClCh – Oreochromis mossabicus<br />
-
 
+
**[[7xa9]] - AtCIC–A - Cryo EM<br />
-
*Calcium-activated chloride channel or anoctamin or scramblase see [[Anoctamin 3D structures]]
+
-
 
+
-
*Calcium-activated chloride channel or bestrophin see [[Bestrophin 3D structures]]
+
*CAMP-dependent chloride channel or cystic fibrosis transmembrane conductance regulator see CFTR in [[ABC transporter 3D structures]]
*CAMP-dependent chloride channel or cystic fibrosis transmembrane conductance regulator see CFTR in [[ABC transporter 3D structures]]
-
* Anion Channel (Outer mitochondrial membrane protein porin 1)
+
*Anion Channel (Outer mitochondrial membrane protein porin 1)
-
**[[2jk4]], [[2k4t]], [[5jdp]], [[5xdo]], [[5xdn]], [[6g73]], [[6g6u]] – hVDAC1<br />
+
**[[2jk4]], [[2k4t]], [[5jdn]], [[5xdo]], [[5xdp]], [[6g6u]], [[6g73]] – hVDAC1
**[[6tiq]] – hVDAC1 – NMR<br />
**[[6tiq]] – hVDAC1 – NMR<br />
**[[7qi2]] – hVDAC1 (mutant) – NMR<br />
**[[7qi2]] – hVDAC1 (mutant) – NMR<br />
**[[6tir]] – hVDAC1 + NAD – NMR<br />
**[[6tir]] – hVDAC1 + NAD – NMR<br />
-
**[[6djb]], [[5zsu]], [[7xzh]] – hVDAC1 subunit LRRC8A – Cryo EM<br />
+
**[[5zsu]], [[6djb]], [[7xzh]] – hVDAC1 subunit LRRC8A – Cryo EM<br />
**[[8dxn]], [[8dxo]], [[8dxp]], [[8dxq]], [[8dxr]] – hVDAC1 subunit LRRC8A + LRRC8C – Cryo EM<br />
**[[8dxn]], [[8dxo]], [[8dxp]], [[8dxq]], [[8dxr]] – hVDAC1 subunit LRRC8A + LRRC8C – Cryo EM<br />
**[[6m04]] – hVDAC1 subunit LRRC8AD (mutant) – Cryo EM<br />
**[[6m04]] – hVDAC1 subunit LRRC8AD (mutant) – Cryo EM<br />
-
[[3emn]], [[4c69]] – mVDAC1 <br />
+
**[[3emn]], [[4c69]], [[9gng]] – mVDAC1 <br />
**[[7kuh]] – mVDAC – electron crystallography <br />
**[[7kuh]] – mVDAC – electron crystallography <br />
-
**[[6g9o]], [[6g9l]], [[6g8z]], [[6o00]], [[6nzz]], [[6nzw]], [[7m17]], [[7m19]] – mVDAC1 subunit LRRC8A – Cryo EM<br />
+
**[[6g8z]], [[6g9l]], [[6g9o]], [[6nzw]], [[6nzz]], [[6o00]], [[7m17]], [[7m19]] – mVDAC1 subunit LRRC8A – Cryo EM<br />
**[[8b40]] – mVDAC1 subunit LRRC8C – Cryo EM<br />
**[[8b40]] – mVDAC1 subunit LRRC8C – Cryo EM<br />
**[[8ben]] – mVDAC1 subunit LRRC8C LRR domain – Cryo EM<br />
**[[8ben]] – mVDAC1 subunit LRRC8C LRR domain – Cryo EM<br />
Line 220: Line 221:
**[[6fnw]] – mVDAC1 subunit LRRC8A C terminal<br />
**[[6fnw]] – mVDAC1 subunit LRRC8A C terminal<br />
**[[4bum]] – zeVDAC2 <br />
**[[4bum]] – zeVDAC2 <br />
-
**[[7en0]] – VDAC1 – ''Brachypodium distachyon'' – Cryo EM<br />
+
**[[7en0]] – VDAC1 – Brachypodium distachyon – Cryo EM<br />
**[[7w6k]] – ALMT – soy bean – Cryo EM<br />
**[[7w6k]] – ALMT – soy bean – Cryo EM<br />
**[[7wnq]] – AtSLAC1 – Cryo EM<br />
**[[7wnq]] – AtSLAC1 – Cryo EM<br />
 +
**[[9jvq]] – yVDAC1– Cryo EM<br />
-
* Ligand-gated ion channel
+
*Ligand-gated ion channel
**[[5osa]], [[5osb]] – mGLIC + GABAAR <br />
**[[5osa]], [[5osb]] – mGLIC + GABAAR <br />
**[[5osc]] – mGLIC + GABAAR + drug<br />
**[[5osc]] – mGLIC + GABAAR + drug<br />
-
**[[2vl0]], [[3rqu]], [[2yn6]] – EchELIC –'' Erwinia chrysanthemi''<br />
+
**[[2vl0]], [[2yn6]], [[3rqu]] – EchELIC – Erwinia chrysanthemi
-
**[[2yks]], [[3uq4]], [[3uq5]], [[3uq7]], [[4twh]], [[5hej]], [[5heo]], [[5heu]], [[5hew]] – EchELIC (mutant)<br />
+
**[[2yks]], [[3uq4]], [[3uq5]], [[3uq7]], [[4twh]], [[5hej]], [[5heo]], [[5heu]], [[5hew]] – EchELIC (mutant)
-
**[[6v03]], [[6v0b]], [[8d63]], [[8d64]], [[8d65]] - EchELIC – Cryo EM<br />
+
**[[6v03]], [[6v0b]], [[8d63]], [[8d64]], [[8d65]], [[8f35]], [[8twz]], [[9ngf]], [[9ngg]], [[9ngq]], [[9ngr]], [[9ngs]] - EchELIC – Cryo EM<br />
-
**[[8d66]], [[8d67]], [[8d68]] – EchELIC3 (mutant) – Cryo EM<br />
+
**[[8d66]], [[8d67]], [[8vuw]] – EchELIC3 (mutant) – Cryo EM<br />
**[[3rqw]] - EchELIC + acetylcholine<br />
**[[3rqw]] - EchELIC + acetylcholine<br />
**[[5sxu]] - EchELIC + bromoethanol<br />
**[[5sxu]] - EchELIC + bromoethanol<br />
Line 237: Line 239:
**[[3zkr]] - EchELIC + anesthetic<br />
**[[3zkr]] - EchELIC + anesthetic<br />
**[[2yoe]] - EchELIC + drug + GABA<br />
**[[2yoe]] - EchELIC + drug + GABA<br />
-
**[[4a97]], [[4a98]], [[5lid]], [[5lg3]] – EchELIC + drug<br />
+
**[[4a97]], [[4a98]], [[5lg3]], [[5lid]] – EchELIC + drug<br />
**[[5sxv]] – EchELIC + inhibitor <br />
**[[5sxv]] – EchELIC + inhibitor <br />
**[[4yeu]] – EchELIC + GLIC <br />
**[[4yeu]] – EchELIC + GLIC <br />
Line 243: Line 245:
**[[6hjx]], [[6hjy]], [[6ssi]], [[6ssp]] – DcELIC + nanobody <br />
**[[6hjx]], [[6hjy]], [[6ssi]], [[6ssp]] – DcELIC + nanobody <br />
**[[6fl9]], [[6fli]], [[6fvq]], [[6fvr]], [[6fvs]] - ELIC – vent tica<br />
**[[6fl9]], [[6fli]], [[6fvq]], [[6fvr]], [[6fvs]] - ELIC – vent tica<br />
-
**[[3eam]], [[3ehz]], [[4hfi]], [[4il4]], [[4ilc]], [[4npp]], [[4npq]], [[4qh1]], [[4qh5]], [[4qh4]], [[6f7a]], [[6f16]], [[4zzc]], [[6hzw]] – GvGLIC - Gloeobacter violaceus<br />
+
**[[3eam]], [[3ehz]], [[4hfi]], [[4il4]], [[4ilc]], [[4npp]], [[4npq]], [[4qh1]], [[4qh4]], [[4qh5]], [[4zzc]], [[6f16]], [[6f7a]], [[6hzw]] – GvGLIC - Gloeobacter violaceus<br />
-
**[[6zgd]], [[6zgj]], [[6zgk]] – GvGLIC – Cryo EM<br />
+
**[[6zgd]], [[6zgj]], [[6zgk]], [[8atg]], [[8i42]], [[8jj3]], [[8wcr]] – GvGLIC – Cryo EM<br />
-
**[[6hk0]] – DcELIC (mutant) – ''Dickeya chrysanthemi''<br />
+
**[[3ei0]], [[3tls]], [[3tlt]], [[3tlu]], [[3tlv]], [[3tlw]], [[3uu3]], [[3uu4]], [[3uu5]], [[3uu6]], [[3uu8]], [[3uub]], [[3lsv]], [[4hfb]], [[4il9]], [[4ila]], [[4ilb]], [[4ire]], [[4lmj]], [[4lmk]], [[4lml]], [[4zzb]], [[5hcj]], [[5hcm]], [[5heg]], [[5heh]], [[5iux]], [[5mzq]], [[5mzr]], [[5mzt]], [[5njy]], [[5nkj]], [[5v6n]], [[5v6o]], [[6emx]], [[6f0i]], [[6f0j]], [[6f0m]], [[6f0n]], [[6f0r]], [[6f0u]], [[6f0v]], [[6f0z]], [[6f10]], [[6f11]], [[6f12]], [[6f13]], [[6f15]], [[6hy5]], [[6hy9]], [[6hya]], [[6hyr]], [[6hyv]], [[6hyw]], [[6hyx]], [[6hyz]], [[6hz0]], [[6hz1]], [[6hz3]], [[6i08]] – GvGLIC (mutant)
-
**[[6hjx]], [[6hjy]], [[6ssi]], [[6ssp]] – DcELIC + nanobody <br />
+
**[[3igq]] – GvGLIC N-terminal
-
**[[6fl9]], [[6fli]], [[6fvq]], [[6fvr]], [[6fvs]] - ELIC – vent tica<br />
+
**[[2xq3]], [[2xq4]], [[2xq5]], [[2xq6]], [[2xq7]], [[2xq8]], [[2xqa]] – GvGLIC+inhibitor
-
**[[3eam]], [[3ehz]], [[4hfi]], [[4il4]], [[4ilc]], [[4npp]], [[4npq]], [[4qh1]], [[4qh5]], [[4qh4]], [[6f7a]], [[6f16]], [[4zzc]], [[6hzw]] – GvGLIC – ''Gloeobacter violaceus''br />
+
**[[2xq9]] – GvGLIC (mutant)+inhibitor
-
**[[3lsv]], [[3tls]], [[3tlt]], [[3tlu]], [[3tlv]], [[3tlw]], [[3uu3]], [[3uu4]], [[3uu5]], [[3uu6]], [[3uu8]], [[3uub]], [[3ei0]], [[4hfb]], [[4il9]], [[4ila]], [[4ilb]], [[4ire]], [[4lmj]], [[4lmk]], [[4lml]], [[5hcj]], [[5hcm]], [[5heg]], [[5heh]], [[5iux]], [[5v6o]], [[5v6n]], [[5nkj]], [[5njy]], [[5mzt]], [[5mzr]], [[5mzq]], [[4zzb]], [[6hy5]], [[6hy9]], [[6hya]], [[6hyr]], [[6hyv]], [[6hyw]], [[6hyx]], [[6hyz]], [[6hz0]], [[6hz1]], [[6hz3]], [[6emx]], [[6f0i]], [[6f0j]], [[6f0m]], [[6f0n]], [[6f0r]], [[6f0u]], [[6f0v]], [[6f0z]], [[6f10]], [[6f11]], [[6f12]], [[6f13]], [[6f15]], [[6f16]], [[6i08]] – GvGLIC (mutant)<br />
+
**[[3p4w]], [[3p50]], [[4f8h]], [[4hfh]] – GvGLIC + general anaesthetic
-
**[[3igq]] – GvGLIC N-terminal<br />
+
**[[4hfd]], [[5mvm]], [[5mvn]], [[5muo]], [[5mur]] – GvGLIC (mutant) + general anaesthetic<br />
-
**[[2xq3]], [[2xq4]], [[2xq5]], [[2xq6]], [[2xq7]], [[2xqa]], [[2xq8]] – GvGLIC+inhibitor <br />
+
-
**[[2xq9]] – GvGLIC (mutant)+inhibitor<br />
+
-
**[[3p4w]], [[3p50]], [[4f8h]], [[4hfh]] – GvGLIC + general anaesthetic<br />
+
-
**[[4hfd]], [[5mvn]], [[5mvm]], [[5mur]], [[5muo]] – GvGLIC (mutant) + general anaesthetic<br />
+
**[[4hfc]], [[4hfe]] - GvGLIC (mutant) + alcohol<br />
**[[4hfc]], [[4hfe]] - GvGLIC (mutant) + alcohol<br />
**[[5j0z]] - GvGLIC + choline derivative<br />
**[[5j0z]] - GvGLIC + choline derivative<br />
**[[5l47]], [[5l4e]], [[5l4h]] - GvGLIC + barbiturate<br />
**[[5l47]], [[5l4e]], [[5l4h]] - GvGLIC + barbiturate<br />
-
**[[6hj3]], [[6hjb]], [[6hji]], [[6hja]], [[6hjz]], [[6hpp]] - GvGLIC + carboxylate<br />
+
**[[6hj3]], [[6hja]], [[6hjb]], [[6hji]], [[6hjz]], [[6hpp]] - GvGLIC + carboxylate<br />
-
**[[6v4a]], [[6v4s]], [[7q3g]] - DeELIC – ''Desulfofustis''<br />
+
**[[6v4a]], [[6v4s]], [[7q3g]] - DeCLIC – Desulfofustis<br />
-
**[[7q3h]] – DeELIC – Cryo EM<br />
+
**[[7q3h]], [[9evb]], [[9ftj]] – DeCLIC – Cryo EM<br />
-
* Cyclic Nucleotide-Gated channel
+
*Cyclic nucleotide-gated channel
**[[7lg1]] – hCNGA1 (mutant) – Cryo EM<br />
**[[7lg1]] – hCNGA1 (mutant) – Cryo EM<br />
Line 272: Line 270:
**[[7rhs]] – hCNGA3 + CNGB3 – Cryo EM<br />
**[[7rhs]] – hCNGA3 + CNGB3 – Cryo EM<br />
**[[3swf]] - bCNGC CLZ domain <br />
**[[3swf]] - bCNGC CLZ domain <br />
-
**[[2zd9]], [[3beh]] - MlCNGC - ''Mesorhizobium loti''<br />
+
**[[2zd9]], [[3beh]] – MlCNGC - Mesorhizobium loti
**[[4chv]], [[4chw]] – MlCNGC – Cryo EM<br />
**[[4chv]], [[4chw]] – MlCNGC – Cryo EM<br />
-
**[[2ptm]] - CNGC C-terminal - ''Strongylocentratus purpuratus''<br />
+
**[[2ptm]] – CNGC C-terminal – Strongylocentrotus purpuratus
-
**[[2kxl]], [[1vp6]] - MlCNGC ligand-binding domain <br />
+
**[[1vp6]], [[2kxl]] - MlCNGC ligand-binding domain <br />
-
**[[3co2]], [[4muv]], [[3clp]], [[1u12]] - MlCNGC ligand-binding domain (mutant) <br />
+
**[[1u12]], [[3clp]], [[3co2]], [[4muv]] - MlCNGC ligand-binding domain (mutant)
-
**[[3cl1]], [[2k0g]] - MlCNGC ligand-binding domain + cyclic nucleotide<br />
+
**[[2k0g]], [[3cl1]] - MlCNGC ligand-binding domain + cyclic nucleotide<br />
**[[5h3o]] – CeCNGC – Cryo EM<br />
**[[5h3o]] – CeCNGC – Cryo EM<br />
**[[6wej]], [[6wek]], [[6wel]] – CeCNGC + cGMP – Cryo EM<br />
**[[6wej]], [[6wek]], [[6wel]] – CeCNGC + cGMP – Cryo EM<br />
-
**[[6cju]], [[6vxz]], [[6vy0]] – StCNGC + cAMP – ''Spitochaeta thermophila'' - Cryo EM<br />
+
**[[6cju]], [[6vxz]], [[6vy0]] – StCNGC + cAMP – Spitochaeta thermophila - Cryo EM<br />
**[[6cjq]] – StCNGC - Cryo EM<br />
**[[6cjq]] – StCNGC - Cryo EM<br />
**[[6cjt]] – StCNGC + cGMP - Cryo EM<br />
**[[6cjt]] – StCNGC + cGMP - Cryo EM<br />
Line 298: Line 296:
**[[7nmn]], [[7np3]] – rCNGC 4 – Cryo EM<br />
**[[7nmn]], [[7np3]] – rCNGC 4 – Cryo EM<br />
**[[7np4]] – rCNGC 4 + cAMP – Cryo EM<br />
**[[7np4]] – rCNGC 4 + cAMP – Cryo EM<br />
-
**[[3etq]], [[3ffq]], [[3u0z]], [[3u10]], [[3u11]] - mCNGC C-terminal<br />
+
**[[3etq]], [[3ffq]], [[3u0z]], [[3u10]], [[3u11]] – mCNGC C-terminal
-
**[[1q3e]], [[1q43]], [[1q5o]] - mCNGC 2 fragment + nucleotide<br />
+
**[[1q3e]], [[1q43]], [[1q5o]] – mCNGC 2 fragment + cyclic nucleotide
-
**[[2q0a]] - mCNGC 2 C-terminal (mutant)<br />
+
**[[2q0a]] – mCNGC C-terminal (mutant)
-
**[[3bpz]] - mCNGC 2 ligand-binding domain <br />
+
**[[3bpz]] – mCNGC ligand-binding domain (mutant)
**[[5khg]], [[5khh]], [[5khi]], [[5khj]], [[5khk]] – mCNGC 2 ligand-binding domain + nucleotide<br />
**[[5khg]], [[5khh]], [[5khi]], [[5khj]], [[5khk]] – mCNGC 2 ligand-binding domain + nucleotide<br />
-
* Acid sensing ion channel
+
*Acid sensing ion channel
**[[6l6i]], [[6l6n]], [[6l6p]] – hASC <br />
**[[6l6i]], [[6l6n]], [[6l6p]] – hASC <br />
-
**[[7cfs]] – hASC – Cryo EM<br />
+
**[[7cfs]] – hASC 1a – Cryo EM<br />
 +
**[[9mlv]] – hASC 5 – Cryo EM<br />
**[[7cft]] – hASC + toxin – Cryo EM<br />
**[[7cft]] – hASC + toxin – Cryo EM<br />
**[[7rnn]] – hASC + nanobody – Cryo EM<br />
**[[7rnn]] – hASC + nanobody – Cryo EM<br />
-
**[[3ij4]], [[2qts]], [[3s3w]], [[4nyk]], [[3ij4]], [[6ave]], [[5wku]], [[5wkv]], [[5wky]], [[5wkx]], [[6cmc]] – cASC – chicken<br />
+
**[[2qts]], [[3ij4]], [[3s3w]], [[4nyk]], [[5wku]], [[5wkv]], [[5wky]], [[5wkx]], [[6ave]], [[6cmc]] – cASC
**[[7lie]] – cASC thumb domain 291-367<br />
**[[7lie]] – cASC thumb domain 291-367<br />
**[[6vtk]], [[6vtl]] – cASC – Cryo EM<br />
**[[6vtk]], [[6vtl]] – cASC – Cryo EM<br />
-
**[[3s3x]], [[4fz0]], [[4fz1]] – cASC + psalmotoxin<br />
+
**[[3s3x]], [[4fz0]], [[4fz1]] – cASC + psalmotoxin
**[[4ntw]], [[4ntx]], [[4nty]] - cASC + neurotoxin + basic phospholipase A2<br />
**[[4ntw]], [[4ntx]], [[4nty]] - cASC + neurotoxin + basic phospholipase A2<br />
**[[6x9h]] – cASC + modulator<br />
**[[6x9h]] – cASC + modulator<br />
-
* ATP-Gated P2X channel (AGC) or P2X purinoceptor
+
*ATP-Gated P2X channel (AGC) or P2X purinoceptor
**[[5svj]], [[5svs]], [[5svt]] – hAGC P2X3 <br />
**[[5svj]], [[5svs]], [[5svt]] – hAGC P2X3 <br />
Line 331: Line 330:
**[[2rup]] – raAGC P2X4 head domain 111-167 – NMR<br />
**[[2rup]] – raAGC P2X4 head domain 111-167 – NMR<br />
**[[5xw6]] – cAGC P2X7 + antagonist<br />
**[[5xw6]] – cAGC P2X7 + antagonist<br />
-
**[[3h9v]], [[3i5d]] – zeAGC P2X4<br />
+
**[[3h9v]], [[3i5d]] – zeAGC P2X4
**[[4dw0]] – zeAGC P2X4 (mutant)<br />
**[[4dw0]] – zeAGC P2X4 (mutant)<br />
**[[4dw1]] – zeAGC P2X4 + ATP<br />
**[[4dw1]] – zeAGC P2X4 + ATP<br />
**[[5wzy]] – zeAGC P2X4 + CTP<br />
**[[5wzy]] – zeAGC P2X4 + CTP<br />
-
* Proton channel or matrix protein 2
+
*Proton channel or matrix protein 2
-
**[[2kj1]], [[2l0j]] - IVproton channel – Influenza virus - NMR<br />
+
**[[2kj1]], [[2l0j]] - IVproton channel cytoplasmic domain – Influenza virus - NMR
-
**[[2kih]], [[2kwx]] – IVproton channel (mutant)<br />
+
**[[2kih]], [[2kwx]] – IVproton channel (mutant)
-
**[[3bkd]], [[4qkm]], [[4qkl]], [[4qkc]], [[4qk7]], [[3lbw]], [[5ttc]], [[5um1]], [[5joo]] - IVproton channel transmembrane domain<br />
+
**[[3bkd]], [[3lbw]], [[4qk7]], [[4qkc]], [[4qkl]], [[4qkm]], [[5joo]], [[5ttc]], [[5um1]] - IVproton channel transmembrane domain
-
**[[1nyj]], [[1mp6]], [[2kad]], [[6pvr]], [[6pvt]] - IVproton channel transmembrane domain - NMR<br />
+
**[[1mp6]], [[1nyj]], [[2kad]], [[6pvr]], [[6pvt]] - IVproton channel transmembrane domain – NMR
-
**[[5c02]], [[4rwc]], [[4rwb]], [[2kih]], [[6mjh]] - IVproton channel transmembrane domain (mutant)<br />
+
**[[4rwb]], [[4rwc]], [[5c02]], [[6mjh]] - IVproton channel transmembrane domain (mutant)<br />
**[[2n70]] - IVproton channel transmembrane domain (mutant) - NMR<br />
**[[2n70]] - IVproton channel transmembrane domain (mutant) - NMR<br />
**[[6bkk]], [[6bkl]], [[6bmz]], [[6boc]], [[6us8]], [[6us9]] - IVproton channel transmembrane domain + drug<br />
**[[6bkk]], [[6bkl]], [[6bmz]], [[6boc]], [[6us8]], [[6us9]] - IVproton channel transmembrane domain + drug<br />
**[[2h95]], [[2kqt]] - IVproton channel transmembrane domain + drug - NMR<br />
**[[2h95]], [[2kqt]] - IVproton channel transmembrane domain + drug - NMR<br />
**[[2ly0]] - IVproton channel transmembrane domain (mutant) + drug - NMR<br />
**[[2ly0]] - IVproton channel transmembrane domain (mutant) + drug - NMR<br />
-
**[[2rlf]] - IVproton channel + inhibitor - NMR<br />
+
**[[2rlf]] - IVproton channel + inhibitor – NMR
-
**[[3c9j]], [[6oug]] - IVproton channel transmembrane domain + inhibitor<br />
+
**[[3c9j]], [[6oug]] - IVproton channel transmembrane domain + inhibitor
**[[6nv1]] - IVproton channel transmembrane domain (mutant) + inhibitor<br />
**[[6nv1]] - IVproton channel transmembrane domain (mutant) + inhibitor<br />
**[[8bdz]], [[8ber]] - proton channel M2 – Hepatitis virus – Cryo EM<br />
**[[8bdz]], [[8ber]] - proton channel M2 – Hepatitis virus – Cryo EM<br />
-
* Voltage-gated hydrogen channel (VGHC)
+
*Voltage-gated hydrogen channel (VGHC)
-
+
 
-
**[[3a2a]] – hVGHC C-terminal - NMR <br />
+
**[[3a2a]] – hVGHC C-terminal – NMR
**[[5oqk]] – hVGHC residues 82-226 - NMR<br />
**[[5oqk]] – hVGHC residues 82-226 - NMR<br />
**[[3wkv]] – mVGHC <br />
**[[3wkv]] – mVGHC <br />
-
**[[3vmx]], [[3vmy]], [[3vmz]] – mVGHC C-terminal<br />
+
**[[3vmx]], [[3vmy]], [[3vmz]] – mVGHC C-terminal
**[[3vn0]], [[3vyi]] – mVGHC C-terminal (mutant)<br />
**[[3vn0]], [[3vyi]] – mVGHC C-terminal (mutant)<br />
-
*'''Transient receptor potential cation channel, vanilloid subfamily (TRPV)'''
+
*Synthetic ion channel
 +
 
 +
**[[8yq5]], [[8yq6]] – SIC – Cryo EM
 +
 
 +
*Transient receptor potential cation channel, vanilloid subfamily (TRPV)
-
*''TRPV1 or capsaicin receptor''
+
*TRPV1 or capsaicin receptor
**[[7lp9]], [[7lpa]], [[7lpc]], [[7lpd]], [[8gf8]], [[8gf9]], [[8gfa]] – hTRPV1 – Cryo EM<br />
**[[7lp9]], [[7lpa]], [[7lpc]], [[7lpd]], [[8gf8]], [[8gf9]], [[8gfa]] – hTRPV1 – Cryo EM<br />
Line 376: Line 379:
**[[7l2h]], [[7l2i]], [[7l2j]], [[7l2k]], [[7l2l]], [[7l2m]], [[7l2n]], [[7l2o]], [[7l2p]], [[7l2r]], [[7l2s]], [[7l2t]], [[7l2u]], [[7l2v]], [[7l2w]], [[7l2x]], [[7lpb]], [[7lpe]], [[7mz5]], [[7mz6]], [[7mz7]], [[7mz9]], [[7mza]], [[7mzb]], [[7mzc]], [[7mzd]], [[7mze]], [[7rqu]], [[7rqv]], [[7rqw]], [[7rqx]], [[7rqy]], [[7rqz]] – raTRPV1 + drug – Cryo EM<br />
**[[7l2h]], [[7l2i]], [[7l2j]], [[7l2k]], [[7l2l]], [[7l2m]], [[7l2n]], [[7l2o]], [[7l2p]], [[7l2r]], [[7l2s]], [[7l2t]], [[7l2u]], [[7l2v]], [[7l2w]], [[7l2x]], [[7lpb]], [[7lpe]], [[7mz5]], [[7mz6]], [[7mz7]], [[7mz9]], [[7mza]], [[7mzb]], [[7mzc]], [[7mzd]], [[7mze]], [[7rqu]], [[7rqv]], [[7rqw]], [[7rqx]], [[7rqy]], [[7rqz]] – raTRPV1 + drug – Cryo EM<br />
-
*''TRPV2''
+
*TRPV2
**[[5hi9]] – hTRPV2 – Cryo EM<br />
**[[5hi9]] – hTRPV2 – Cryo EM<br />
**[[2f37]], [[4n5q]] – hTRPV2 ankyrin repeat domain 69-367<br />
**[[2f37]], [[4n5q]] – hTRPV2 ankyrin repeat domain 69-367<br />
-
**[[2eta]], [[2etb]], [[2etc]] – rTRPV2 ankyrin repeat domain - rat<br />
+
**[[2eta]], [[2etb]], [[2etc]] – raTRPV2 ankyrin repeat domain <br />
-
**[[6bo4]], [[6bo5]], [[6u84]], [[6u86]] – rTRPV2 – Cryo EM<br />
+
**[[6bo4]], [[6bo5]], [[6u84]], [[6u86]] – raTRPV2 – Cryo EM<br />
**[[6wkn]], [[7n0m]], [[7n0n]], [[7t37]], [[7t38]], [[7zjh]], [[8slx]], [[8sly]] – raTRPV2 + cannabidiol – Cryo EM<br />
**[[6wkn]], [[7n0m]], [[7n0n]], [[7t37]], [[7t38]], [[7zjh]], [[8slx]], [[8sly]] – raTRPV2 + cannabidiol – Cryo EM<br />
**[[6u88]], [[6u8a]] – rTRPV2 + cannabidiol – Cryo EM<br />
**[[6u88]], [[6u8a]] – rTRPV2 + cannabidiol – Cryo EM<br />
-
**[[6bwm]] – raTRPV2 – rabbit<br />
+
**[[6bwm]] – rTRPV2 <br />
-
**[[5an8]], [[6oo3]], [[6oo4]], [[6oo5]], [[6oo7]] – raTRPV2 – Cryo EM<br />
+
**[[5an8]], [[6oo3]], [[6oo4]], [[6oo5]], [[6oo7]] – rTRPV2 – Cryo EM<br />
-
**[[6bwj]] – raTRPV2 (mutant) + resiniferatoxin<br />
+
**[[6bwj]] – rTRPV2 (mutant) + resiniferatoxin<br />
-
**[[6b5v]] – raTRPV2 + inhibitor – Cryo EM<br />
+
**[[6b5v]] – rTRPV2 + inhibitor – Cryo EM<br />
**[[7xeu]] – mTRPV2 – Cryo EM<br />
**[[7xeu]] – mTRPV2 – Cryo EM<br />
**[[7xer]], [[7xew]] – mTRPV2 (mutant) – Cryo EM<br />
**[[7xer]], [[7xew]] – mTRPV2 (mutant) – Cryo EM<br />
**[[7xem]] – mTRPV2 + cholesterol – Cryo EM<br />
**[[7xem]] – mTRPV2 + cholesterol – Cryo EM<br />
-
**[[7xeo]], [[7xev]], [[7yep]] – mTRPV2 + ligand – Cryo EM<br />
+
**[[7xeo]], [[7xep]], [[7yev]] – mTRPV2 + ligand – Cryo EM<br />
-
*''TRPV3''
+
*TRPV3
-
**[[6mho]], [[6mhs]], [[6mhv]], [[6mhw]], [[6mhx]], [[6uw4]] – hTRPV3 – Cryo EM<br />
+
**[[6mho]], [[6mhs]], [[6mhv]], [[6mhw]], [[6mhx]], [[6uw4]], [[7xj3]] – hTRPV3 – Cryo EM<br />
**[[6ot2]], [[6uw6]], [[6uw8]], [[6uw9]] – hTRPV3 (mutant) – Cryo EM<br />
**[[6ot2]], [[6uw6]], [[6uw8]], [[6uw9]] – hTRPV3 (mutant) – Cryo EM<br />
**[[6ot5]] – hTRPV3 (mutant) + inhibitor – Cryo EM<br />
**[[6ot5]] – hTRPV3 (mutant) + inhibitor – Cryo EM<br />
**[[7xj0]] – hTRPV3 + drug – Cryo EM<br />
**[[7xj0]] – hTRPV3 + drug – Cryo EM<br />
-
**[[6dvw]], [[6dvy]], [[6lgp]], [[6pvl]], [[6pvm]], [[7mik]] – mTRPV3 – Cryo EM<br />
+
**[[6dvw]], [[6dvy]], [[6lgp]], [[6pvl]], [[6pvm]] – mTRPV3 – Cryo EM<br />
**[[7mij]], [[7mik]], [[7mil]], [[7mim]], [[7min]], [[7mio]], [[7ras]], [[7rau]], [[7ugg]] – mTRPV3 + drug – Cryo EM<br />
**[[7mij]], [[7mik]], [[7mil]], [[7mim]], [[7min]], [[7mio]], [[7ras]], [[7rau]], [[7ugg]] – mTRPV3 + drug – Cryo EM<br />
**[[6dvz]], [[6pvn]], [[6pvp]], [[6pvo]], [[6pvq]] – mTRPV3 (mutant) – Cryo EM<br />
**[[6dvz]], [[6pvn]], [[6pvp]], [[6pvo]], [[6pvq]] – mTRPV3 (mutant) – Cryo EM<br />
**[[4n5q]] – mTRPV3 ankyrin repeat domain 118-367<br />
**[[4n5q]] – mTRPV3 ankyrin repeat domain 118-367<br />
-
*''TRPV4''
+
*TRPV4
**[[7aa5]] – hTRPV4 + agonist – Cryo EM<br />
**[[7aa5]] – hTRPV4 + agonist – Cryo EM<br />
Line 413: Line 416:
**[[3w9f]] – cTRPV4 ankyrin repeat domain + inositol-3-phosphate<br />
**[[3w9f]] – cTRPV4 ankyrin repeat domain + inositol-3-phosphate<br />
-
*''TRPV5''
+
*TRPV5
**[[5oeo]] – hTRPV5 655-725 + calmodulin – NMR<br />
**[[5oeo]] – hTRPV5 655-725 + calmodulin – NMR<br />
**[[6dmr]], [[6dmu]], [[6o1n]], [[6o1p]], [[6pbe]], [[6pbf]], [[7t6j]], [[7t6k]], [[7t6l]], [[7t6m]], [[7t6n]], [[7t6o]] – rTRPV5 – Cryo EM<br />
**[[6dmr]], [[6dmu]], [[6o1n]], [[6o1p]], [[6pbe]], [[6pbf]], [[7t6j]], [[7t6k]], [[7t6l]], [[7t6m]], [[7t6n]], [[7t6o]] – rTRPV5 – Cryo EM<br />
**[[6o1u]], [[7t6p]], [[7t6q]], [[7t6r]] – rTRPV5 (mutant) – Cryo EM<br />
**[[6o1u]], [[7t6p]], [[7t6q]], [[7t6r]] – rTRPV5 (mutant) – Cryo EM<br />
-
**[[6dmw]], [[6o20]] – raTRPV5 + calmodulin – Cryo EM<br />
+
**[[6dmw]], [[6o20]] – rTRPV5 + calmodulin – Cryo EM<br />
-
*''TRPV6''
+
*TRPV6
**[[6bo8]], [[6bo9]], [[7k4a]], [[8fob]] – hTRPV6 – Cryo EM<br />
**[[6bo8]], [[6bo9]], [[7k4a]], [[8fob]] – hTRPV6 – Cryo EM<br />
Line 432: Line 435:
**[[2rfa]] – mTRPV6 ankyrin repeat domain 44-265<br />
**[[2rfa]] – mTRPV6 ankyrin repeat domain 44-265<br />
**[[7d2k]] – raTRPV6 + inhibitor – Cryo EM<br />
**[[7d2k]] – raTRPV6 + inhibitor – Cryo EM<br />
 +
 +
*Transient receptor potential cation channel (TRPM)
 +
 +
*TRPM2
 +
 +
**[[8e6q]], [[8e6r]], [[8e6s]] – hTRPM2 – Cryo EM<br />
 +
 +
*TRPM3
 +
 +
**[[8ddq]], [[8ddr]], [[8ddt]], [[8ddu]], [[8ed8]] – mTRPM3 – Cryo EM<br />
 +
**[[8ddx]] – mTRPM3 + G proteins – Cryo EM<br />
 +
 +
*Short transient receptor potential channel 5 (TRPC5)
 +
 +
*TRPC5
 +
 +
**[[7e4t]], [[7x6c]], [[8gvw]], [[9m36]] – hTRPC5 – Cryo EM<br />
 +
**[[7d4p]], [[7wdb]], [[9m4w]], [[9m5v]] – hTRPC5 + drug – Cryo EM<br />
 +
**[[7x6i]], [[8gvx]] – hTRPC5 + G proteins – Cryo EM<br />
 +
**[[9gkb]], [[9gl6]] – hTRPC5 + ligand – Cryo EM<br />
 +
**[[9g4y]], [[9g50]] – hTRPC5 + photoswitch – Cryo EM<br />
 +
**[[6aei]] – mTRPC5 – Cryo EM<br />
*Glycerol facilitator
*Glycerol facilitator
-
**[[1lda]], [[1ldi]] - EcGlpF<br />
+
**[[1lda]], [[1ldi]] – EcGlpF
-
**[[1fx8]] - EcGlpF + glycerol<br />
+
**[[1fx8]] – EcGlpF + glycerol
**[[1ldf]] - EcGlpF (mutant)
**[[1ldf]] - EcGlpF (mutant)
 +
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D structures of ion channels

Updated on 08-October-2025


Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Jaime Prilusky

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