8pmz

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Current revision (08:43, 14 July 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8pmz is ON HOLD until Paper Publication
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==HEV gt3 P domain in complex with glycan-insensitive nAb p61.15==
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<StructureSection load='8pmz' size='340' side='right'caption='[[8pmz]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8pmz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Orthohepevirus_A Orthohepevirus A]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PMZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PMZ FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.912&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B3P:2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>B3P</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pmz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pmz OCA], [https://pdbe.org/8pmz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pmz RCSB], [https://www.ebi.ac.uk/pdbsum/8pmz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pmz ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/C4B4T9_HEV C4B4T9_HEV] Forms an icosahedral capsid with a T=1 symmetry and a 34 nm diameter. The capsid is composed of 60 copies linked to each other. Binds to the 5' end of the genomic RNA to mediate genome encapsidation.[RuleBase:RU363023] Plays a role in the inhibition of host antibody-mediated neutralization without blocking viral cell entry.[RuleBase:RU363023]
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Orthohepevirus A]]
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[[Category: Krey T]]
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[[Category: Ssebyatika G]]

Current revision

HEV gt3 P domain in complex with glycan-insensitive nAb p61.15

PDB ID 8pmz

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