8q4l
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8q4l is ON HOLD Authors: Pfleiderer, M.M., Liu, X., Fisch, D., Anastasakou, E., Frickel, E.M., Galej, W.P. Description: GBP1 bound by 14-3-3sigma [...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==GBP1 bound by 14-3-3sigma== | |
| - | + | <StructureSection load='8q4l' size='340' side='right'caption='[[8q4l]], [[Resolution|resolution]] 5.12Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8q4l]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Q4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Q4L FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 5.12Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8q4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8q4l OCA], [https://pdbe.org/8q4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8q4l RCSB], [https://www.ebi.ac.uk/pdbsum/8q4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8q4l ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Frickel | + | [https://www.uniprot.org/uniprot/GBP1_HUMAN GBP1_HUMAN] Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.<ref>PMID:22106366</ref> |
| - | [[Category: Galej | + | == References == |
| - | [[Category: Liu | + | <references/> |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Anastasakou E]] | ||
| + | [[Category: Fisch D]] | ||
| + | [[Category: Frickel EM]] | ||
| + | [[Category: Galej WP]] | ||
| + | [[Category: Liu X]] | ||
| + | [[Category: Pfleiderer MM]] | ||
Current revision
GBP1 bound by 14-3-3sigma
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