8q4q
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of YTHDC1 in complex with Compound 29 (ZA_337)== | |
| - | + | <StructureSection load='8q4q' size='340' side='right'caption='[[8q4q]], [[Resolution|resolution]] 1.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8q4q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Q4Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Q4Q FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JIB:4-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]benzoic+acid'>JIB</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8q4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8q4q OCA], [https://pdbe.org/8q4q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8q4q RCSB], [https://www.ebi.ac.uk/pdbsum/8q4q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8q4q ProSAT]</span></td></tr> |
| - | [[Category: Bedi | + | </table> |
| - | [[Category: Zalesak | + | == Function == |
| + | [https://www.uniprot.org/uniprot/YTDC1_HUMAN YTDC1_HUMAN] RNA-binding protein that regulates alternative splice site selection.<ref>PMID:20167602</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bedi RK]] | ||
| + | [[Category: Caflisch A]] | ||
| + | [[Category: Zalesak F]] | ||
Current revision
Crystal structure of YTHDC1 in complex with Compound 29 (ZA_337)
<StructureSection load='8q4q' size='340' side='right'caption='8q4q, resolution 1.40Å' scene=>
Structural highlights
| 8q4q is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. | |
| Method: | X-ray diffraction, Resolution 1.4Å |
| Ligands: | <scene name='pdbligand=JIB:4-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]benzoic+acid'>JIB</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
YTDC1_HUMAN RNA-binding protein that regulates alternative splice site selection.[1]
References
- ↑ Zhang Z, Theler D, Kaminska KH, Hiller M, de la Grange P, Pudimat R, Rafalska I, Heinrich B, Bujnicki JM, Allain FH, Stamm S. The YTH domain is a novel RNA binding domain. J Biol Chem. 2010 May 7;285(19):14701-10. doi: 10.1074/jbc.M110.104711. Epub 2010, Feb 18. PMID:20167602 doi:http://dx.doi.org/10.1074/jbc.M110.104711
Contents |
</StructureSection>
