8q5c

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "8q5c" [edit=sysop:move=sysop])
Current revision (14:47, 19 February 2025) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8q5c is ON HOLD
+
==Ternary structure of 14-3-3s, C-RAF phosphopeptide (pS259) and compound 12 (1075475)==
-
 
+
<StructureSection load='8q5c' size='340' side='right'caption='[[8q5c]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
Authors: Konstantinidou, M., Vickery, H., Pennings, M.A.M., Virta, J., Visser, E.J., Oetelaar, M.C.M., Overmans, M., Neitz, J., Ottmann, C., Brunsveld, L., Arkin, M.R.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[8q5c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Q5C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Q5C FirstGlance]. <br>
-
Description: Ternary structure of 14-3-3s, C-RAF phosphopeptide (pS259) and compound 12 (1075475)
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=W5T:~{N}-[[1-(4-chlorophenyl)sulfonylpiperidin-4-yl]methyl]ethanamide'>W5T</scene></td></tr>
-
[[Category: Konstantinidou, M]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8q5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8q5c OCA], [https://pdbe.org/8q5c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8q5c RCSB], [https://www.ebi.ac.uk/pdbsum/8q5c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8q5c ProSAT]</span></td></tr>
-
[[Category: Virta, J]]
+
</table>
-
[[Category: Overmans, M]]
+
== Function ==
-
[[Category: Ottmann, C]]
+
[https://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.
-
[[Category: Neitz, J]]
+
__TOC__
-
[[Category: Arkin, M.R]]
+
</StructureSection>
-
[[Category: Visser, E.J]]
+
[[Category: Homo sapiens]]
-
[[Category: Pennings, M.A.M]]
+
[[Category: Large Structures]]
-
[[Category: Brunsveld, L]]
+
[[Category: Arkin MR]]
-
[[Category: Oetelaar, M.C.M]]
+
[[Category: Brunsveld L]]
-
[[Category: Vickery, H]]
+
[[Category: Konstantinidou M]]
 +
[[Category: Neitz J]]
 +
[[Category: Oetelaar MCM]]
 +
[[Category: Ottmann C]]
 +
[[Category: Overmans M]]
 +
[[Category: Pennings MAM]]
 +
[[Category: Vickery H]]
 +
[[Category: Virta J]]
 +
[[Category: Visser EJ]]

Current revision

Ternary structure of 14-3-3s, C-RAF phosphopeptide (pS259) and compound 12 (1075475)

PDB ID 8q5c

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/8q5c"
Personal tools