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8q6o
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==X. laevis CMG dimer bound to dimeric DONSON - without ATPase== | |
| - | + | <StructureSection load='8q6o' size='340' side='right'caption='[[8q6o]], [[Resolution|resolution]] 3.14Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8q6o]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Q6O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Q6O FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.14Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8q6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8q6o OCA], [https://pdbe.org/8q6o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8q6o RCSB], [https://www.ebi.ac.uk/pdbsum/8q6o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8q6o ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PSF1_XENLA PSF1_XENLA] Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.<ref>PMID:12730133</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Xenopus laevis]] | ||
| + | [[Category: Butryn A]] | ||
| + | [[Category: Costa A]] | ||
| + | [[Category: Cvetkovic MA]] | ||
Current revision
X. laevis CMG dimer bound to dimeric DONSON - without ATPase
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