8pxw

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Current revision (05:49, 3 April 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8pxw is ON HOLD until Paper Publication
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==Structure of the WW domain tandem of PRPF40A==
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<StructureSection load='8pxw' size='340' side='right'caption='[[8pxw]]' scene=''>
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Authors: Martinez-Lumbreras, S., Sattler, M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8pxw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PXW FirstGlance]. <br>
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Description: Structure of the WW domain tandem of PRPF40A
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pxw OCA], [https://pdbe.org/8pxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pxw RCSB], [https://www.ebi.ac.uk/pdbsum/8pxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pxw ProSAT]</span></td></tr>
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[[Category: Sattler, M]]
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</table>
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[[Category: Martinez-Lumbreras, S]]
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== Function ==
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[https://www.uniprot.org/uniprot/PR40A_HUMAN PR40A_HUMAN] Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing.<ref>PMID:21834987</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Martinez-Lumbreras S]]
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[[Category: Sattler M]]

Current revision

Structure of the WW domain tandem of PRPF40A

PDB ID 8pxw

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