8q8g
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8q8g is ON HOLD Authors: Petit, A.P., Fyfe, P.K. Description: Crystal structure of HsRNMT complexed with inhibitor DDD1870799 [[Category: Unrelease...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of HsRNMT complexed with inhibitor DDD1870799== | |
| - | + | <StructureSection load='8q8g' size='340' side='right'caption='[[8q8g]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8q8g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Q8G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Q8G FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8q8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8q8g OCA], [https://pdbe.org/8q8g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8q8g RCSB], [https://www.ebi.ac.uk/pdbsum/8q8g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8q8g ProSAT]</span></td></tr> |
| - | [[Category: Fyfe | + | </table> |
| - | [[Category: Petit | + | == Function == |
| + | [https://www.uniprot.org/uniprot/MCES_HUMAN MCES_HUMAN] mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC.<ref>PMID:9790902</ref> <ref>PMID:9705270</ref> <ref>PMID:10347220</ref> <ref>PMID:22099306</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fyfe PK]] | ||
| + | [[Category: Petit AP]] | ||
Current revision
Crystal structure of HsRNMT complexed with inhibitor DDD1870799
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