8twx

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(New page: '''Unreleased structure''' The entry 8twx is ON HOLD Authors: Lee, K.H., Lee, S.H., Paige, M., Noble, S.M. Description: Synthesis and Evaluation of Diaryl Ether Modulators of the Leuko...)
Current revision (05:21, 28 August 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8twx is ON HOLD
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==Synthesis and Evaluation of Diaryl Ether Modulators of the Leukotriene A4 Hydrolase Aminopeptidase Activity==
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<StructureSection load='8twx' size='340' side='right'caption='[[8twx]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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Authors: Lee, K.H., Lee, S.H., Paige, M., Noble, S.M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8twx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TWX FirstGlance]. <br>
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Description: Synthesis and Evaluation of Diaryl Ether Modulators of the Leukotriene A4 Hydrolase Aminopeptidase Activity
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8twx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8twx OCA], [https://pdbe.org/8twx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8twx RCSB], [https://www.ebi.ac.uk/pdbsum/8twx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8twx ProSAT]</span></td></tr>
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[[Category: Lee, S.H]]
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</table>
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[[Category: Paige, M]]
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== Function ==
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[[Category: Noble, S.M]]
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[https://www.uniprot.org/uniprot/LKHA4_HUMAN LKHA4_HUMAN] Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.<ref>PMID:1897988</ref> <ref>PMID:1975494</ref> <ref>PMID:2244921</ref> <ref>PMID:12207002</ref> <ref>PMID:11917124</ref> <ref>PMID:15078870</ref> <ref>PMID:18804029</ref>
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[[Category: Lee, K.H]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Lee KH]]
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[[Category: Lee SH]]
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[[Category: Noble SM]]
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[[Category: Paige M]]

Current revision

Synthesis and Evaluation of Diaryl Ether Modulators of the Leukotriene A4 Hydrolase Aminopeptidase Activity

PDB ID 8twx

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