8qcb
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==CryoEM structure of a S. Cerevisiae Ski2387 complex in the open state== | |
- | + | <StructureSection load='8qcb' size='340' side='right'caption='[[8qcb]], [[Resolution|resolution]] 2.80Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[8qcb]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QCB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QCB FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8Å</td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qcb OCA], [https://pdbe.org/8qcb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qcb RCSB], [https://www.ebi.ac.uk/pdbsum/8qcb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qcb ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/SKI2_YEAST SKI2_YEAST] RNA helicase component of the SKI complex involved in 3'-mRNA degradation pathway. Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A). Essential for cell growth only in the presence of M1 replicon.<ref>PMID:8321235</ref> <ref>PMID:363683</ref> <ref>PMID:6371496</ref> <ref>PMID:7739552</ref> <ref>PMID:7739557</ref> <ref>PMID:9482746</ref> <ref>PMID:10611222</ref> <ref>PMID:10744028</ref> <ref>PMID:10922069</ref> <ref>PMID:11532933</ref> <ref>PMID:11720286</ref> <ref>PMID:12769863</ref> <ref>PMID:14671320</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Saccharomyces cerevisiae]] | ||
+ | [[Category: Conti E]] | ||
+ | [[Category: Keidel A]] | ||
+ | [[Category: Koegel A]] | ||
+ | [[Category: Kowalinski E]] | ||
+ | [[Category: Reichelt P]] | ||
+ | [[Category: Schaefer IB]] |
Current revision
CryoEM structure of a S. Cerevisiae Ski2387 complex in the open state
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