8w8f

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'''Unreleased structure'''
 
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The entry 8w8f is ON HOLD
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==human co-transcriptional RNA capping enzyme RNGTT-CMTR1==
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<StructureSection load='8w8f' size='340' side='right'caption='[[8w8f]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
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Authors: Li, Y., Wang, Q., Xu, Y., Li, Z.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8w8f]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8W8F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8W8F FirstGlance]. <br>
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Description: human co-transcriptional RNA capping enzyme RNGTT-CMTR1
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Li, Y]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8w8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8w8f OCA], [https://pdbe.org/8w8f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8w8f RCSB], [https://www.ebi.ac.uk/pdbsum/8w8f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8w8f ProSAT]</span></td></tr>
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[[Category: Xu, Y]]
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</table>
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[[Category: Li, Z]]
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== Function ==
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[[Category: Wang, Q]]
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[https://www.uniprot.org/uniprot/MCE1_HUMAN MCE1_HUMAN] Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Sus scrofa]]
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[[Category: Li Y]]
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[[Category: Li Z]]
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[[Category: Wang Q]]
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[[Category: Xu Y]]

Current revision

human co-transcriptional RNA capping enzyme RNGTT-CMTR1

PDB ID 8w8f

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