8qb9

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'''Unreleased structure'''
 
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The entry 8qb9 is ON HOLD until Paper Publication
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==Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture -PIP2/+sterol (DOPC, DOPE, DOPS, cholesterol 30:20:20:30)==
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<StructureSection load='8qb9' size='340' side='right'caption='[[8qb9]], [[Resolution|resolution]] 3.35&Aring;' scene=''>
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Authors: Kefauver, J.M., Zou, L., Desfosses, A., Loewith, R.J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8qb9]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QB9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QB9 FirstGlance]. <br>
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Description: Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture -PIP2/+sterol (DOPC, DOPE, DOPS, cholesterol 30:20:20:30)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.35&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qb9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qb9 OCA], [https://pdbe.org/8qb9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qb9 RCSB], [https://www.ebi.ac.uk/pdbsum/8qb9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qb9 ProSAT]</span></td></tr>
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[[Category: Loewith, R.J]]
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</table>
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[[Category: Zou, L]]
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== Function ==
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[[Category: Desfosses, A]]
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[https://www.uniprot.org/uniprot/PIL1_YEAST PIL1_YEAST] Negative regulator of cell wall integrity (CWI) in unstressed cells, probably by inhibiting protein kinase PKH1/PHK2 activity and regulating their downstream CWI pathways PKC1-MAP kinase pathway and protein kinase YPK1 pathway. Activity may be regulated by the transient increase of sphingolipid long chain bases (LCBs) during heat stress.<ref>PMID:15016821</ref>
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[[Category: Kefauver, J.M]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Desfosses A]]
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[[Category: Kefauver JM]]
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[[Category: Loewith RJ]]
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[[Category: Zou L]]

Current revision

Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture -PIP2/+sterol (DOPC, DOPE, DOPS, cholesterol 30:20:20:30)

PDB ID 8qb9

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