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8qmo
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8qmo is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex== | |
| - | + | <StructureSection load='8qmo' size='340' side='right'caption='[[8qmo]], [[Resolution|resolution]] 2.76Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8qmo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QMO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QMO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.76Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MOO:MOLYBDATE+ION'>MOO</scene>, <scene name='pdbligand=W62:benzo[a]pyrene'>W62</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qmo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qmo OCA], [https://pdbe.org/8qmo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qmo RCSB], [https://www.ebi.ac.uk/pdbsum/8qmo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qmo ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HS90B_HUMAN HS90B_HUMAN] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:16478993</ref> <ref>PMID:19696785</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ancelin A]] | ||
| + | [[Category: Bourguet W]] | ||
| + | [[Category: Carivenc C]] | ||
| + | [[Category: Grandvuillemin L]] | ||
| + | [[Category: Gruszczyk J]] | ||
| + | [[Category: Hesketh EL]] | ||
| + | [[Category: Kwong HS]] | ||
| + | [[Category: Lai-Kee-Him J]] | ||
| + | [[Category: Lancey C]] | ||
| + | [[Category: Ragan TJ]] | ||
| + | [[Category: Sirounian S]] | ||
Current revision
Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex
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Categories: Homo sapiens | Large Structures | Ancelin A | Bourguet W | Carivenc C | Grandvuillemin L | Gruszczyk J | Hesketh EL | Kwong HS | Lai-Kee-Him J | Lancey C | Ragan TJ | Sirounian S
