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8u0x

From Proteopedia

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Current revision (14:11, 29 November 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8u0x is ON HOLD until Paper Publication
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==Yeast Pex6 N1(1-184) Domain==
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<StructureSection load='8u0x' size='340' side='right'caption='[[8u0x]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8u0x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8U0X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8U0X FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8u0x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8u0x OCA], [https://pdbe.org/8u0x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8u0x RCSB], [https://www.ebi.ac.uk/pdbsum/8u0x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8u0x ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PEX6_YEAST PEX6_YEAST] Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling (PubMed:15634331, PubMed:16007078, PubMed:16911527, PubMed:26170309, PubMed:26066397, PubMed:29321502). Specifically recognizes PEX5 monoubiquitinated at 'Cys-6', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel (PubMed:26170309, PubMed:26066397, PubMed:29321502). Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5 (PubMed:29321502).<ref>PMID:15634331</ref> <ref>PMID:16007078</ref> <ref>PMID:16911527</ref> <ref>PMID:26066397</ref> <ref>PMID:26170309</ref> <ref>PMID:29321502</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Ali BA]]
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[[Category: Gardner BM]]

Current revision

Yeast Pex6 N1(1-184) Domain

PDB ID 8u0x

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