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1n7a

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[[Image:1n7a.gif|left|200px]]
 
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==RIP-Radiation-damage Induced Phasing==
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The line below this paragraph, containing "STRUCTURE_1n7a", creates the "Structure Box" on the page.
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<StructureSection load='1n7a' size='340' side='right'caption='[[1n7a]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1n7a]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N7A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N7A FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGM:8-BROMO-2-DEOXYGUANOSINE-5-MONOPHOSPHATE'>BGM</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
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{{STRUCTURE_1n7a| PDB=1n7a | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n7a OCA], [https://pdbe.org/1n7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n7a RCSB], [https://www.ebi.ac.uk/pdbsum/1n7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n7a ProSAT]</span></td></tr>
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</table>
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'''RIP-Radiation-damage Induced Phasing'''
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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==Overview==
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[[Category: Caffrey M]]
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The use of third generation synchrotron sources has led to renewed concern about the effect of ionizing radiation on crystalline biological samples. In general, the problem is seen as one to be avoided. However, in this paper, it is shown that, far from being a hindrance to successful structure determination, radiation damage provides an opportunity for phasing macromolecular structures. This is successfully demonstrated for both a protein and an oligonucleotide, by way of which complete models were built automatically. The possibility that, through the exploitation of radiation damage, the phase problem could become less of a barrier to macromolecular crystal structure determination is discussed.
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[[Category: Leiros H-KS]]
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[[Category: McSweeney S]]
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==About this Structure==
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[[Category: Pan B]]
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N7A OCA].
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[[Category: Ravelli RBG]]
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==Reference==
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Specific radiation damage can be used to solve macromolecular crystal structures., Ravelli RB, Leiros HK, Pan B, Caffrey M, McSweeney S, Structure. 2003 Feb;11(2):217-24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12575941 12575941]
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[[Category: Caffrey, M.]]
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[[Category: Leiros, H K.S.]]
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[[Category: McSweeney, S.]]
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[[Category: Pan, B.]]
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[[Category: Ravelli, R B.G.]]
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[[Category: Dna]]
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[[Category: Rna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:11:01 2008''
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Current revision

RIP-Radiation-damage Induced Phasing

PDB ID 1n7a

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