1n7v

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:53, 14 February 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1n7v.jpg|left|200px]]
 
-
<!--
+
==THE RECEPTOR-BINDING PROTEIN P2 OF BACTERIOPHAGE PRD1: CRYSTAL FORM III==
-
The line below this paragraph, containing "STRUCTURE_1n7v", creates the "Structure Box" on the page.
+
<StructureSection load='1n7v' size='340' side='right'caption='[[1n7v]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1n7v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacteria_phage_PRD1 Enterobacteria phage PRD1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N7V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N7V FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-
{{STRUCTURE_1n7v| PDB=1n7v | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n7v OCA], [https://pdbe.org/1n7v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n7v RCSB], [https://www.ebi.ac.uk/pdbsum/1n7v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n7v ProSAT]</span></td></tr>
-
 
+
</table>
-
'''THE RECEPTOR-BINDING PROTEIN P2 OF BACTERIOPHAGE PRD1: CRYSTAL FORM III'''
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/P2_BPPRD P2_BPPRD] Adsorption protein. In association with P31 and trimeric P5, forms the spike complexes located at the 5-fold vertices of the capsid. Involved in recognition and attachment to the receptor on the surface of the host. Likely triggers the processes of vertex disassembly, membrane tube formation, and subsequent DNA injection. Essential for viral infectivity.<ref>PMID:11577098</ref>
-
 
+
== References ==
-
==Overview==
+
<references/>
-
Bacteriophage PRD1 is unusual, with an internal lipid membrane, but has striking resemblances to adenovirus that include receptor binding spikes. The PRD1 vertex complex contains P2, a 590 residue monomer that binds to receptors on antibiotic-resistant strains of E. coli and so is the functional counterpart to adenovirus fiber. P2 structures from two crystal forms, at 2.2 and 2.4 A resolution, reveal an elongated club-shaped molecule with a novel beta propeller "head" showing pseudo-6-fold symmetry. An extended loop with another novel fold forms a long "tail" containing a protruding proline-rich "fin." The head and fin structures are well suited to recognition and attachment, and the tail is likely to trigger the processes of vertex disassembly, membrane tube formation, and subsequent DNA injection.
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Enterobacteria phage PRD1]]
-
1N7V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_prd1 Enterobacteria phage prd1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N7V OCA].
+
[[Category: Large Structures]]
-
 
+
[[Category: Bamford DH]]
-
==Reference==
+
[[Category: Benson SD]]
-
The receptor binding protein P2 of PRD1, a virus targeting antibiotic-resistant bacteria, has a novel fold suggesting multiple functions., Xu L, Benson SD, Butcher SJ, Bamford DH, Burnett RM, Structure. 2003 Mar;11(3):309-22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12623018 12623018]
+
[[Category: Burnett RM]]
-
[[Category: Enterobacteria phage prd1]]
+
[[Category: Butcher SJ]]
-
[[Category: Single protein]]
+
[[Category: Xu L]]
-
[[Category: Bamford, D H.]]
+
-
[[Category: Benson, S D.]]
+
-
[[Category: Burnett, R M.]]
+
-
[[Category: Butcher, S J.]]
+
-
[[Category: Xu, L.]]
+
-
[[Category: Antibiotic-resistance]]
+
-
[[Category: Bacteriophage prd1]]
+
-
[[Category: Beta-propeller]]
+
-
[[Category: Proline-rich]]
+
-
[[Category: Viral receptor-binding]]
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:12:21 2008''
+

Current revision

THE RECEPTOR-BINDING PROTEIN P2 OF BACTERIOPHAGE PRD1: CRYSTAL FORM III

PDB ID 1n7v

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1n7v"
Personal tools