8h3q
From Proteopedia
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== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/CAND1_HUMAN CAND1_HUMAN] Enhances transcription from various types of promoters (By similarity). Regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. Prevents neddylation of CUL1 by physically blocking access to the neddylation site. Disrupts interactions between CUL1 and SKP1 and between CUL1 and F-box proteins.<ref>PMID:12504026</ref> <ref>PMID:12504025</ref> <ref>PMID:12609982</ref> | [https://www.uniprot.org/uniprot/CAND1_HUMAN CAND1_HUMAN] Enhances transcription from various types of promoters (By similarity). Regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. Prevents neddylation of CUL1 by physically blocking access to the neddylation site. Disrupts interactions between CUL1 and SKP1 and between CUL1 and F-box proteins.<ref>PMID:12504026</ref> <ref>PMID:12504025</ref> <ref>PMID:12609982</ref> | ||
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| + | ==See Also== | ||
| + | *[[CAND1 3D structures|CAND1 3D structures]] | ||
| + | *[[Ring box protein 3D structures|Ring box protein 3D structures]] | ||
| + | *[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Current revision
Cryo-EM Structure of the CAND1-Cul3-Rbx1 complex
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Categories: Homo sapiens | Large Structures | Chen Z | Hu Y | Mao Q | Sun L
