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8qjz
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of E. coli LpxH in complex with lipid X== | |
| - | + | <StructureSection load='8qjz' size='340' side='right'caption='[[8qjz]], [[Resolution|resolution]] 1.35Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8qjz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QJZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QJZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LP5:(R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL)+3-HYDROXYTETRADECANOATE'>LP5</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr> |
| - | [[Category: Bergfors | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qjz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qjz OCA], [https://pdbe.org/8qjz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qjz RCSB], [https://www.ebi.ac.uk/pdbsum/8qjz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qjz ProSAT]</span></td></tr> |
| - | [[Category: Jones | + | </table> |
| - | [[Category: Mowbray | + | == Function == |
| - | [[Category: Sooriyaarachchi | + | [https://www.uniprot.org/uniprot/A0A066QL39_ECOLX A0A066QL39_ECOLX] Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.[HAMAP-Rule:MF_00575] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bergfors T]] | ||
| + | [[Category: Jones TA]] | ||
| + | [[Category: Mowbray SL]] | ||
| + | [[Category: Sooriyaarachchi S]] | ||
Current revision
Crystal structure of E. coli LpxH in complex with lipid X
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