7ljx
From Proteopedia
(Difference between revisions)
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<StructureSection load='7ljx' size='340' side='right'caption='[[7ljx]], [[Resolution|resolution]] 1.31Å' scene=''> | <StructureSection load='7ljx' size='340' side='right'caption='[[7ljx]], [[Resolution|resolution]] 1.31Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'> | + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LJX FirstGlance]. <br> |
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.31Å</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.31Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FC6:HEXACYANOFERRATE(3-)'>FC6</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr> | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FC6:HEXACYANOFERRATE(3-)'>FC6</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ljx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ljx OCA], [https://pdbe.org/7ljx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ljx RCSB], [https://www.ebi.ac.uk/pdbsum/7ljx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ljx ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ljx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ljx OCA], [https://pdbe.org/7ljx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ljx RCSB], [https://www.ebi.ac.uk/pdbsum/7ljx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ljx ProSAT]</span></td></tr> | ||
</table> | </table> | ||
- | == Function == | ||
- | [https://www.uniprot.org/uniprot/CYC_RAT CYC_RAT] Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: Rattus norvegicus]] | ||
[[Category: Brunzelle JS]] | [[Category: Brunzelle JS]] | ||
[[Category: Edwards BFP]] | [[Category: Edwards BFP]] | ||
[[Category: Huttemann M]] | [[Category: Huttemann M]] | ||
[[Category: Vaishnav A]] | [[Category: Vaishnav A]] |
Current revision
Oxidized rat cytochrome c mutant (K53Q)
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