8k3z

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:22, 17 July 2024) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8k3z is ON HOLD until Paper Publication
+
==Cryo-EM structure of CXCR4 in complex with CXCL12==
-
 
+
<StructureSection load='8k3z' size='340' side='right'caption='[[8k3z]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
-
Authors: Liu, Y.Z., Liu, A.J., Liao, Q.W.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[8k3z]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Vicugna_pacos Vicugna pacos]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8K3Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8K3Z FirstGlance]. <br>
-
Description: Cryo-EM structure of CXCR4 in complex with CXCL12
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.81&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8k3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8k3z OCA], [https://pdbe.org/8k3z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8k3z RCSB], [https://www.ebi.ac.uk/pdbsum/8k3z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8k3z ProSAT]</span></td></tr>
-
[[Category: Liu, Y.Z]]
+
</table>
-
[[Category: Liu, A.J]]
+
== Function ==
-
[[Category: Liao, Q.W]]
+
[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Vicugna pacos]]
 +
[[Category: Liao QW]]
 +
[[Category: Liu AJ]]
 +
[[Category: Liu YZ]]
 +
[[Category: Ye RD]]

Current revision

Cryo-EM structure of CXCR4 in complex with CXCL12

PDB ID 8k3z

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/8k3z"
Personal tools