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1no5

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[[Image:1no5.jpg|left|200px]]
 
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==Structure of HI0073 from Haemophilus influenzae, the nucleotide binding domain of the HI0073/HI0074 two protein nucleotidyl transferase.==
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The line below this paragraph, containing "STRUCTURE_1no5", creates the "Structure Box" on the page.
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<StructureSection load='1no5' size='340' side='right'caption='[[1no5]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1no5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NO5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NO5 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1no5| PDB=1no5 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1no5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1no5 OCA], [https://pdbe.org/1no5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1no5 RCSB], [https://www.ebi.ac.uk/pdbsum/1no5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1no5 ProSAT]</span></td></tr>
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</table>
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'''Structure of HI0073 from Haemophilus influenzae, the nucleotide binding domain of the HI0073/HI0074 two protein nucleotidyl transferase.'''
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== Function ==
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[https://www.uniprot.org/uniprot/MNTA_HAEIN MNTA_HAEIN] Probable antitoxin component of a type VII toxin-antitoxin (TA) system. Neutralizes cognate toxic HEPN probably by di-AMPylation (Probable). A mixture of HepT and MntA binds nucleotides; the highest affinity is for TTP, ATP binds more tightly than ADP or AMP (PubMed:16028221).<ref>PMID:16028221</ref> <ref>PMID:29555683</ref>
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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1NO5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NO5 OCA].
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Check<jmol>
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<jmolCheckbox>
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==Reference==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/no/1no5_consurf.spt"</scriptWhenChecked>
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Structure of HI0073 from Haemophilus influenzae, the nucleotide-binding domain of a two-protein nucleotidyl transferase., Lehmann C, Pullalarevu S, Krajewski W, Willis MA, Galkin A, Howard A, Herzberg O, Proteins. 2005 Sep 1;60(4):807-11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16028221 16028221]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1no5 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Galkin, A.]]
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[[Category: Galkin A]]
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[[Category: Herzberg, O.]]
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[[Category: Herzberg O]]
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[[Category: Howard, A.]]
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[[Category: Howard A]]
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[[Category: Krajewski, W.]]
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[[Category: Krajewski W]]
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[[Category: Lehmann, C.]]
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[[Category: Lehmann C]]
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[[Category: Pullalarevu, S.]]
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[[Category: Pullalarevu S]]
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[[Category: S2F, Structure 2.Function Project.]]
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[[Category: Willis MA]]
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[[Category: Willis, M A.]]
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[[Category: Hi0073]]
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[[Category: Hi0074]]
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[[Category: Nucleotidyl transferase]]
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[[Category: S2f]]
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[[Category: Structural genomic]]
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[[Category: Structure 2 function project]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:46:13 2008''
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Current revision

Structure of HI0073 from Haemophilus influenzae, the nucleotide binding domain of the HI0073/HI0074 two protein nucleotidyl transferase.

PDB ID 1no5

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