8qqd
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==CryoEM structure of the type IV pilin PilA4 from Thermus thermophilus== | |
| - | + | <StructureSection load='8qqd' size='340' side='right'caption='[[8qqd]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8qqd]] is a 45 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QQD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QQD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.4Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=WT8:6-(1-acetamido-2-oxidanyl-propyl)-5-(ethanimidoylamino)-2,4-bis(oxidanyl)oxane-2-carboxylic+acid'>WT8</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qqd OCA], [https://pdbe.org/8qqd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qqd RCSB], [https://www.ebi.ac.uk/pdbsum/8qqd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qqd ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PILA4_THET2 PILA4_THET2] Plays an essential role in the assembly of two types of T4P pili: a wide and a narrow that participate in natural transformation and twitching motility (PubMed:32376942). Major component of the wide pilus that is essential for natural transformation working as a DNA translocator structure that spans the inner and outer membranes (PubMed:12839734, PubMed:16857013, PubMed:19396940, PubMed:32376942). In addition, participates in the assembly of the narrow pilus composed of the PilA5 subunit that is required for twitching motility (PubMed:32376942).<ref>PMID:12839734</ref> <ref>PMID:16857013</ref> <ref>PMID:19396940</ref> <ref>PMID:32376942</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Thermus thermophilus]] | ||
| + | [[Category: Gaines M]] | ||
| + | [[Category: Gold VAM]] | ||
| + | [[Category: Isupov M]] | ||
| + | [[Category: McLaren M]] | ||
| + | [[Category: Neuhaus A]] | ||
Current revision
CryoEM structure of the type IV pilin PilA4 from Thermus thermophilus
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