1nye

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[[Image:1nye.gif|left|200px]]
 
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==Crystal structure of OsmC from E. coli==
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The line below this paragraph, containing "STRUCTURE_1nye", creates the "Structure Box" on the page.
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<StructureSection load='1nye' size='340' side='right'caption='[[1nye]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1nye]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NYE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NYE FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nye FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nye OCA], [https://pdbe.org/1nye PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nye RCSB], [https://www.ebi.ac.uk/pdbsum/1nye PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nye ProSAT], [https://www.topsan.org/Proteins/BSGC/1nye TOPSAN]</span></td></tr>
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{{STRUCTURE_1nye| PDB=1nye | SCENE= }}
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</table>
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== Function ==
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'''Crystal structure of OsmC from E. coli'''
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[https://www.uniprot.org/uniprot/OSMC_ECOLI OSMC_ECOLI] Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide.<ref>PMID:14627744</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==Overview==
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Check<jmol>
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The crystal structure of an osmotically inducible protein (OsmC) from Escherichia coli has been determined at 2.4 A resolution. OsmC is a representative protein of the OsmC sequence family, which is composed of three sequence subfamilies. The structure of OsmC provides a view of a salt-shock-induced protein. Two identical monomers form a cylindrically shaped dimer in which six helices are located on the inside and two six-stranded beta-sheets wrap around these helices. Structural comparison suggests that the OsmC sequence family has a peroxiredoxin function and has a unique structure compared with other peroxiredoxin families. A detailed analysis of structures and sequence comparisons in the OsmC sequence family revealed that each subfamily has unique motifs. In addition, the molecular function of the OsmC sequence family is discussed based on structural comparisons among the subfamily members.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ny/1nye_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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1NYE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NYE OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==Reference==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nye ConSurf].
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Structure of OsmC from Escherichia coli: a salt-shock-induced protein., Shin DH, Choi IG, Busso D, Jancarik J, Yokota H, Kim R, Kim SH, Acta Crystallogr D Biol Crystallogr. 2004 May;60(Pt 5):903-11. Epub 2004, Apr 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15103136 15103136]
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: BSGC, Berkeley Structural Genomics Center.]]
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[[Category: Busso D]]
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[[Category: Busso, D.]]
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[[Category: Choi I-G]]
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[[Category: Choi, I G.]]
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[[Category: Jancarik J]]
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[[Category: Jancarik, J.]]
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[[Category: Kim R]]
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[[Category: Kim, R.]]
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[[Category: Kim S-H]]
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[[Category: Kim, S H.]]
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[[Category: Shin DH]]
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[[Category: Shin, D H.]]
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[[Category: Yokota H]]
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[[Category: Yokota, H.]]
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[[Category: Berkeley structural genomics center]]
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[[Category: Bsgc structure funded by nih]]
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[[Category: Crystal structure]]
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[[Category: Osmc]]
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[[Category: Peroxiredoxin]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 03:08:09 2008''
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Current revision

Crystal structure of OsmC from E. coli

PDB ID 1nye

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