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8uh0
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==SOS2 co-crystal structure with fragment bound (compound 10)== | |
| - | + | <StructureSection load='8uh0' size='340' side='right'caption='[[8uh0]], [[Resolution|resolution]] 2.73Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8uh0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UH0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UH0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.73Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=WRN:8-hydroxyquinoline-2-carbonitrile'>WRN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8uh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8uh0 OCA], [https://pdbe.org/8uh0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8uh0 RCSB], [https://www.ebi.ac.uk/pdbsum/8uh0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8uh0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/SOS2_HUMAN SOS2_HUMAN] Noonan syndrome. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SOS2_HUMAN SOS2_HUMAN] Promotes the exchange of Ras-bound GDP by GTP.[UniProtKB:Q62245] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gunn RJ]] | ||
| + | [[Category: Lawson JD]] | ||
Current revision
SOS2 co-crystal structure with fragment bound (compound 10)
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