8usr
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8usr is ON HOLD until Paper Publication Authors: Argiriadi, M.A., Ramos, A.L. Description: IL17A homodimer complexed to Compound 23 [[Category: Unr...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==IL17A homodimer complexed to Compound 23== | |
| - | + | <StructureSection load='8usr' size='340' side='right'caption='[[8usr]], [[Resolution|resolution]] 1.83Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8usr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8USR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8USR FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.83Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XCE:~{N}-[(2~{S})-1-[[(1~{S})-1-(8~{a}~{H}-imidazo[1,2-a]pyrimidin-2-yl)ethyl]amino]-1-oxidanylidene-4-phenyl-butan-2-yl]-4,5-bis(chloranyl)-1~{H}-pyrrole-2-carboxamide'>XCE</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8usr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8usr OCA], [https://pdbe.org/8usr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8usr RCSB], [https://www.ebi.ac.uk/pdbsum/8usr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8usr ProSAT]</span></td></tr> |
| - | [[Category: Argiriadi | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IL17_HUMAN IL17_HUMAN] Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Argiriadi MA]] | ||
| + | [[Category: Ramos AL]] | ||
Current revision
IL17A homodimer complexed to Compound 23
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