RNA polymerase 3D structures

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**[[7ccg]] - RNAP subunit δ - ''Streptomyces albulus''<br />
**[[7ccg]] - RNAP subunit δ - ''Streptomyces albulus''<br />
**[[7ok0]], [[7oqy]] – SaRNAP – ''Sulfolobus acidocaldarius'' – Cryo EM<br />
**[[7ok0]], [[7oqy]] – SaRNAP – ''Sulfolobus acidocaldarius'' – Cryo EM<br />
-
**[[8h02]] – SeRNAP subunit ’ – Synechococcus elongatus<br />
+
**[[8h02]] – SeRNAP subunit – ''Synechococcus elongatus''<br />
-
**[[8emb]] – RNAP subunit ’ si3 domain – Thermosynechococcus vestitus<br />
+
**[[8emb]] – RNAP subunit ’ si3 domain – ''Thermosynechococcus vestitus''<br />
-
**[[8dkc]] – RNAP subunits ’ Porphyromonas gingivalis – Cryo EM<br />
+
**[[8dkc]] – RNAP subunits α,β,β',ω - ''Porphyromonas gingivalis'' – Cryo EM<br />
*Prokaryotic DNA-dependent RNAP complex with DNA/RNA or elongation complex
*Prokaryotic DNA-dependent RNAP complex with DNA/RNA or elongation complex
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**[[4v8s]] – SsRNAP + DNA<br />
**[[4v8s]] – SsRNAP + DNA<br />
**[[3q22]], [[3q23]], [[3q24]], [[4ff1]], [[4ff2]], [[4ff3]], [[4ff4]] – RNAP + DNA – Enterobacteria phage N4<br />
**[[3q22]], [[3q23]], [[3q24]], [[4ff1]], [[4ff2]], [[4ff3]], [[4ff4]] – RNAP + DNA – Enterobacteria phage N4<br />
-
**[[2o5i]], [[2o5j]], [[4gzy]], [[4gzz]], [[4xln]], [[4xlr]] – TtRNAP subunits ’ + DNA +RNA<br />
+
**[[2o5i]], [[2o5j]], [[4gzy]], [[4gzz]], [[4xln]], [[4xlr]] – TtRNAP subunits α,β,β',ω + DNA +RNA<br />
**[[6m6c]], [[8hsg]], [[8hsr]] - TtRNAP in elongation complex – Cryo EM<br />
**[[6m6c]], [[8hsg]], [[8hsr]] - TtRNAP in elongation complex – Cryo EM<br />
-
**[[5x22]] - TtRNAP subunits ’ + DNA + RNA + CMPCPP<br />
+
**[[5x22]] - TtRNAP subunits α,β,β',ω + DNA + RNA + CMPCPP<br />
-
**[[5x21]] - TtRNAP subunits ’ + DNA + RNA + antibiotic<br />
+
**[[5x21]] - TtRNAP subunits α,β,β',ω + DNA + RNA + antibiotic<br />
-
**[[4wqs]], [[4xlp]], [[4xlq]], [[4xls]], [[5tjg]] - TtRNAP subunits ’ + DNA<br />
+
**[[4wqs]], [[4xlp]], [[4xlq]], [[4xls]], [[5tjg]] - TtRNAP subunits α,β,β',ω + DNA<br />
-
**[[2ppb]] - TtRNAP subunits ’ + antibiotic + DNA + RNA + substrate analog<br />
+
**[[2ppb]] - TtRNAP subunits α,β,β',ω + antibiotic + DNA + RNA + substrate analog<br />
-
**[[4yg2]], [[4jk1]], [[4jk2]], [[4jkr]], [[4kmu]] - EcRNAP subunits ’ RNA<br />
+
**[[4yg2]], [[4jk1]], [[4jk2]], [[4jkr]], [[4kmu]] - EcRNAP subunits α,β,β',ω + RNA<br />
**[[8aby]], [[8ac0]], [[8acp]], [[8ad1]] - EcRNAP in elongation complex + RNA putL – Cryo EM<br />
**[[8aby]], [[8ac0]], [[8acp]], [[8ad1]] - EcRNAP in elongation complex + RNA putL – Cryo EM<br />
**[[6flp]], [[6bjs]], [[6asx]], [[6alh]], [[6alf]], [[6rip]], [[6ri9]], [[7q0j]], [[7q0k]], [[7tyb]], [[7xue]], [[7xug]], [[7yp9]], [[8abz]], [[8ac1]], [[8ac2]], [[8eg7]], [[8eg8]], [[8egb]], [[8eh8]] , [[8eh9]], [[8eha]], [[8ehf]], [[8ehi]], [[8f1i]], [[8f1k]], [[8f3c]], [[8fix]], [[8fiy]], [[8fvr]], [[8fvw]], [[8g00]], [[8g1s]], [[8g2w]], [[8g7e]], [[8pbl]] - EcRNAP in elongation complex – Cryo EM<br />
**[[6flp]], [[6bjs]], [[6asx]], [[6alh]], [[6alf]], [[6rip]], [[6ri9]], [[7q0j]], [[7q0k]], [[7tyb]], [[7xue]], [[7xug]], [[7yp9]], [[8abz]], [[8ac1]], [[8ac2]], [[8eg7]], [[8eg8]], [[8egb]], [[8eh8]] , [[8eh9]], [[8eha]], [[8ehf]], [[8ehi]], [[8f1i]], [[8f1k]], [[8f3c]], [[8fix]], [[8fiy]], [[8fvr]], [[8fvw]], [[8g00]], [[8g1s]], [[8g2w]], [[8g7e]], [[8pbl]] - EcRNAP in elongation complex – Cryo EM<br />
**[[7ypa]] - EcRNAP in transcription-termination complex – Cryo EM<br />
**[[7ypa]] - EcRNAP in transcription-termination complex – Cryo EM<br />
-
**[[6rh3]] - EcRNAP subunits ’ RNA + DNA + GMP + CTP – Cryo EM<br />
+
**[[6rh3]] - EcRNAP subunits α,β,β',ω + RNA + DNA + GMP + CTP – Cryo EM<br />
-
**[[4kn4]], [[4kn7]] - EcRNAP subunits ’ RNA + antibiotic<br />
+
**[[4kn4]], [[4kn7]] - EcRNAP subunits α,β,β',ω + RNA + antibiotic<br />
**[[6vvv]] – MsRNAP in translation initiation complex <br />
**[[6vvv]] – MsRNAP in translation initiation complex <br />
**[[7p5x]] – MsRNAP in translation initiation complex + PafBC – Cryo EM<br />
**[[7p5x]] – MsRNAP in translation initiation complex + PafBC – Cryo EM<br />
-
**[[6vvx]], [[6vvy]], [[6vvs]], [[6vvt]], [[6vvz]] – MsRNAP subunits ’ DNA + antibiotic<br />
+
**[[6vvx]], [[6vvy]], [[6vvs]], [[6vvt]], [[6vvz]] – MsRNAP subunits α,β,β',ω + DNA + antibiotic<br />
-
**[[7l7b]] – RNAP subunits ’ sigma factor SIGA + antibiotic – Clostridia difficalis – Cryo EM<br />
+
**[[7l7b]] – RNAP subunits α,β,β',ω + sigma factor SIGA + antibiotic – ''Clostridia difficalis'' – Cryo EM<br />
-
**[[8gzg]], [[8gzh]] – RNAP elongation complex sigma factor SIGA – Synechocystic – Cryo EM<br />
+
**[[8gzg]], [[8gzh]] – RNAP elongation complex + sigma factor SIGA – ''Synechocystic'' – Cryo EM<br />
*''Prokaryotic DNA-dependent RNAP complex with protein''
*''Prokaryotic DNA-dependent RNAP complex with protein''
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**[[3mmp]] - EcRNAP subunit β + EF-TU<br />
**[[3mmp]] - EcRNAP subunit β + EF-TU<br />
**[[7egs]] - EcRNAP subunit β + DNA helicase II 654-720<br />
**[[7egs]] - EcRNAP subunit β + DNA helicase II 654-720<br />
-
**[[4ljz]], [[4lk1]], [[4mey]], [[4xsx]], [[4xsy]], [[4xsz]], [[4zh2]], [[4zh3]] , [[4zh4]], [[5byh]], [[5nwt]], [[5uag]], [[5uah]], [[5uaj]], [[5ual]], [[5uaq]], [[5ui8]] - EcRNAP subunits α,β,β’,ω + σ factor <br />
+
**[[4ljz]], [[4lk1]], [[4mey]], [[4xsx]], [[4xsy]], [[4xsz]], [[4zh2]], [[4zh3]] , [[4zh4]], [[5nwt]], [[5uag]], [[5uah]], [[5uaj]], [[5ual]], [[5uaq]], [[5ui8]] - EcRNAP subunits α,β,β’,ω + σ factor <br />
**[[6c9y]] - EcRNAP subunits α,β,β’,ω + σ factor – Cryo EM<br />
**[[6c9y]] - EcRNAP subunits α,β,β’,ω + σ factor – Cryo EM<br />
**[[4mex]] - EcRNAP subunits α,β,β’,ω + σ factor + salinamide<br />
**[[4mex]] - EcRNAP subunits α,β,β’,ω + σ factor + salinamide<br />
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**[[5uhf]], [[5uhe]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA + inhibitor<br />
**[[5uhf]], [[5uhe]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA + inhibitor<br />
**[[1l9z]] - TaRNAP subunits α,β,β’,ω + σ factor + DNA<br />
**[[1l9z]] - TaRNAP subunits α,β,β’,ω + σ factor + DNA<br />
-
**[[8i23]], [[8i24]] - RNAP subunits α,β,β’,ω + σ factor SIGI1 + DNA – Clostridium thermocellum - Cryo EM<br />
+
**[[8i23]], [[8i24]] - RNAP subunits α,β,β’,ω + σ factor SIGI1 + DNA – ''Clostridium thermocellum'' - Cryo EM<br />
*''Prokaryotic DNA-dependent RNAP complex with protein + DNA/RNA''
*''Prokaryotic DNA-dependent RNAP complex with protein + DNA/RNA''
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**[[7d7c]] - EcRNAP subunits α,β,β’,ω + GP55 + DNA - Cryo EM<br />
**[[7d7c]] - EcRNAP subunits α,β,β’,ω + GP55 + DNA - Cryo EM<br />
**[[7d7d]] - EcRNAP subunits α,β,β’,ω + DNAP clamp + GP55 + DNA - Cryo EM<br />
**[[7d7d]] - EcRNAP subunits α,β,β’,ω + DNAP clamp + GP55 + DNA - Cryo EM<br />
-
**[[6n4c]], [[6oul]], [[6wr6]], [[6wr8]], [[7n4e]] - EcRNAP subunits α,β,β’,ω + RPOD + DNA – Cryo EM<br />
+
**[[6n4c]], [[6oul]], [[7khc]], [[7khb]], [[7n4e]] - EcRNAP subunits α,β,β’,ω + RPOD + DNA – Cryo EM<br />
**[[7szj]], [[7szk]] - EcRNAP subunits α,β,β’,ω + RPOD + DNA + drug – Cryo EM<br />
**[[7szj]], [[7szk]] - EcRNAP subunits α,β,β’,ω + RPOD + DNA + drug – Cryo EM<br />
**[[6ldi]] - EcRNAP subunits α,β,β’,ω + RPOD + CUER + DNA + RNA – Cryo EM<br />
**[[6ldi]] - EcRNAP subunits α,β,β’,ω + RPOD + CUER + DNA + RNA – Cryo EM<br />
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**[[7kin]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RBPA – Cryo EM<br />
**[[7kin]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RBPA – Cryo EM<br />
**[[7kif]], [[7kim]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RBPA + CARD + Whib7 – Cryo EM<br />
**[[7kif]], [[7kim]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RBPA + CARD + Whib7 – Cryo EM<br />
-
**[[6wmp]] - FtRNAP subunits α,β,β’,ω + RNA + DNA – Francisella tularensis - Cryo EM<br />
+
**[[6wmp]] - FtRNAP subunits α,β,β’,ω + RNA + DNA – ''Francisella tularensis'' - Cryo EM<br />
**[[6wmr]], [[6wmt]] - FtRNAP subunits α,β,β’,ω + σ factor-binding protein PROD + starvation protein + macrophage growth locus + DNA - Cryo EM<br />
**[[6wmr]], [[6wmt]] - FtRNAP subunits α,β,β’,ω + σ factor-binding protein PROD + starvation protein + macrophage growth locus + DNA - Cryo EM<br />
**[[6wvj]] - BsRNAP in elongation complex - Cryo EM<br />
**[[6wvj]] - BsRNAP in elongation complex - Cryo EM<br />
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**[[7w82]] – cRNAP II - maize<br />
**[[7w82]] – cRNAP II - maize<br />
**[[7w88]] – cRNAP II – Cryo EM<br />
**[[7w88]] – cRNAP II – Cryo EM<br />
-
**[[7rqs]] - AtRNAP II – Arabidopsis thaliana - Cryo EM<br />
+
**[[7rqs]] - AtRNAP II – ''Arabidopsis thaliana'' - Cryo EM<br />
-
**[[8h40]] – RNAP II + NtcA – anabaena – Cryo EM<br />
+
**[[8h40]] – RNAP II + NtcA – ''anabaena'' – Cryo EM<br />
**[[1nik]], [[1nt9]], [[1wcm]], [[2b8k]], [[3fki]], [[3qt1]], [[1i3q]], [[1i50]], [[1dzf]], [[5ip7]], [[5ip9]], [[5u5q]] – yRNAP II<br />
**[[1nik]], [[1nt9]], [[1wcm]], [[2b8k]], [[3fki]], [[3qt1]], [[1i3q]], [[1i50]], [[1dzf]], [[5ip7]], [[5ip9]], [[5u5q]] – yRNAP II<br />
**[[3j1n]], [[4v1n]], [[5fmf]], [[5x51]], [[5x50]], [[5x4z]], [[7ozo]], [[7ozp]] – yRNAP II – Cryo EM<br />
**[[3j1n]], [[4v1n]], [[5fmf]], [[5x51]], [[5x50]], [[5x4z]], [[7ozo]], [[7ozp]] – yRNAP II – Cryo EM<br />
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**[[5vvr]] - yRNAP II + DNA + RNA + Rad26 – Cryo EM<br />
**[[5vvr]] - yRNAP II + DNA + RNA + Rad26 – Cryo EM<br />
**[[6upx]], [[6upy]], [[6upz]], [[6uq0]], [[6uq1]], [[6uq2]], [[6uq3]], [[7rim]], [[7rip]], [[7riq]] [[7riw]], [[7rix]], [[7riy]] - yRNAP II in elongation complex<br />
**[[6upx]], [[6upy]], [[6upz]], [[6uq0]], [[6uq1]], [[6uq2]], [[6uq3]], [[7rim]], [[7rip]], [[7riq]] [[7riw]], [[7rix]], [[7riy]] - yRNAP II in elongation complex<br />
-
**[[6a5v]], [[6a5u]], [[6a5t]], [[6a5r]], [[6a5p]], [[6a5o]], [[6a5l]], [[7nkx]], [[7nky]] – yRNAP II + DNA + RNA + nucleosome – Cryo EM<br />
+
**[[6inq]], [[6a5u]], [[6a5t]], [[6a5r]], [[6a5p]], [[6a5o]], [[6a5l]], [[7nkx]], [[7nky]] – yRNAP II + DNA + RNA + nucleosome – Cryo EM<br />
**[[7ml0]], [[7ml1]], [[7ml2]], [[7ml4]], [[7o4i]], [[7o4j]], [[7o4k]], [[7o4l]], [[7o72]], [[7o73]], [[7o75]] - yRNAP II + DNA + TFIIH + TBP – Cryo EM<br />
**[[7ml0]], [[7ml1]], [[7ml2]], [[7ml4]], [[7o4i]], [[7o4j]], [[7o4k]], [[7o4l]], [[7o72]], [[7o73]], [[7o75]] - yRNAP II + DNA + TFIIH + TBP – Cryo EM<br />
**[[7kpv]] – yRNAP II cyclin-like subunit in Cdk8 kinase module – Cryo EM<br />
**[[7kpv]] – yRNAP II cyclin-like subunit in Cdk8 kinase module – Cryo EM<br />
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**[[8att]], [[8atv]], [[8atw]], [[8c5s]], [[8c5u]], [[8q63]] – yRNAP in transcription initiation complex + RNA – Cryo EM<br />
**[[8att]], [[8atv]], [[8atw]], [[8c5s]], [[8c5u]], [[8q63]] – yRNAP in transcription initiation complex + RNA – Cryo EM<br />
**[[8ap1]] – yRNAP in transcription initiation complex + GTP – Cryo EM<br />
**[[8ap1]] – yRNAP in transcription initiation complex + GTP – Cryo EM<br />
- 
*''Eukaryotic DNA primase''
*''Eukaryotic DNA primase''
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**[[2lzn]] – SaDNAP C terminal – NMR<br />
**[[2lzn]] – SaDNAP C terminal – NMR<br />
**[[5guj]] – BsdnaG RNAP domain <br />
**[[5guj]] – BsdnaG RNAP domain <br />
-
**[[6gt7]] – SiDNAP PRN1 helix bundle domain – Sulfolobus islandicus - NMR<br />
+
**[[6gt7]] – SiDNAP PRN1 helix bundle domain – ''Sulfolobus islandicus'' - NMR<br />
**[[6gvu]] – SiDNAP PRN1 helix bundle domain + DNA - NMR<br />
**[[6gvu]] – SiDNAP PRN1 helix bundle domain + DNA - NMR<br />
**[[6gvq]], [[6gvt]] – SiDNAP PRN1 helix bundle domain + DNA + ATP - NMR<br />
**[[6gvq]], [[6gvt]] – SiDNAP PRN1 helix bundle domain + DNA + ATP - NMR<br />
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**[[4m4w]] - GsdnaG helicase binding domain + helicase + DnaI<br />
**[[4m4w]] - GsdnaG helicase binding domain + helicase + DnaI<br />
**[[3b39]] – EcdnaG catalytic domain + DNA<br />
**[[3b39]] – EcdnaG catalytic domain + DNA<br />
-
**[[7t22]], [[7t23]] – EcdnaG C-terminal (mutant) + helicase + DNA – Cryo EM<br />
+
**[[7t22]], [[9eco]] – EcdnaG C-terminal (mutant) + helicase + DNA – Cryo EM<br />
**[[5w36]], [[5w35]], [[5w34]] - MtudnaG + DNA<br />
**[[5w36]], [[5w35]], [[5w34]] - MtudnaG + DNA<br />
**[[1v34]] - PhDNAP small subunit + UTP<br />
**[[1v34]] - PhDNAP small subunit + UTP<br />
**[[4edg]], [[4edk]], [[4edr]], [[4edt]], [[4edv]], [[4ee1]] – SaDNAP + nucleotide<br />
**[[4edg]], [[4edk]], [[4edr]], [[4edt]], [[4edv]], [[4ee1]] – SaDNAP + nucleotide<br />
**[[5of3]] - SsDNAP small + large subunit + protein<br />
**[[5of3]] - SsDNAP small + large subunit + protein<br />
-
**[[7uy8]] - DNAP small + large subunits + DNA polymerase α catalytic+B subunits – Tetrahymena thermophile - Cryo EM<br />
+
**[[7uy8]] - DNAP small + large subunits + DNA polymerase α catalytic+B subunits – ''Tetrahymena thermophile'' - Cryo EM<br />
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**[[4chd]] – TvRNAP 627 domain <br />
**[[4chd]] – TvRNAP 627 domain <br />
**[[4che]], [[4chf]] – TvRNAP cap-binding domain <br />
**[[4che]], [[4chf]] – TvRNAP cap-binding domain <br />
-
**[[5fsw]] - NvRNAP C terminal – Thielavia terrestris<br />
+
**[[5fsw]] - RNAP C terminal – ''Thielavia terrestris''<br />
-
**[[5hsb]] – RNAP – Andes virus<br />
+
**[[6q99]] – RNAP – Andes virus<br />
**[[5ize]] – HavRNAP L – Hantaan virus<br />
**[[5ize]] – HavRNAP L – Hantaan virus<br />
**[[8c4s]] – HavRNAP L – Cryo EM<br />
**[[8c4s]] – HavRNAP L – Cryo EM<br />

Current revision

Updated on 21-December-2024 - For a general description of the protein see RNA polymerase



Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Jaime Prilusky

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