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8r3f
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==C-terminal Rel-homology Domain of NFAT1== | |
| - | + | <StructureSection load='8r3f' size='340' side='right'caption='[[8r3f]], [[Resolution|resolution]] 1.55Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8r3f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8R3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8R3F FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XS8:(4~{S})-6-fluoranyl-3,4-dihydro-2~{H}-chromen-4-amine'>XS8</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8r3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8r3f OCA], [https://pdbe.org/8r3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8r3f RCSB], [https://www.ebi.ac.uk/pdbsum/8r3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8r3f ProSAT]</span></td></tr> |
| - | [[Category: Boettcher | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NFAC2_HUMAN NFAC2_HUMAN] Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.<ref>PMID:21871017</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Boettcher J]] | ||
| + | [[Category: Zak KM]] | ||
Current revision
C-terminal Rel-homology Domain of NFAT1
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