8x0n
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The molecular mechanism of hnRNPA1 recognize TERRA RNA.== |
| - | + | <StructureSection load='8x0n' size='340' side='right'caption='[[8x0n]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8x0n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8X0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8X0N FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8x0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8x0n OCA], [https://pdbe.org/8x0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8x0n RCSB], [https://www.ebi.ac.uk/pdbsum/8x0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8x0n ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN] Amyotrophic lateral sclerosis;Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref> The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN] Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication.<ref>PMID:17229681</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Li F]] | ||
| + | [[Category: Liu Y]] | ||
| + | [[Category: Xu ZY]] | ||
Current revision
The molecular mechanism of hnRNPA1 recognize TERRA RNA.
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Categories: Homo sapiens | Large Structures | Li F | Liu Y | Xu ZY
