8gw6
From Proteopedia
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(Replacing page with ''''Unreleased structure''' The entry 8gw6 is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures') |
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- | '''Unreleased structure''' | ||
- | + | ==AtSLAC1 6D mutant in closed state== | |
- | + | <StructureSection load='8gw6' size='340' side='right'caption='[[8gw6]], [[Resolution|resolution]] 3.30Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[8gw6]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GW6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GW6 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3Å</td></tr> | |
- | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gw6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gw6 OCA], [https://pdbe.org/8gw6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gw6 RCSB], [https://www.ebi.ac.uk/pdbsum/8gw6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gw6 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/SLAC1_ARATH SLAC1_ARATH] Slow, weak voltage-dependent S-type anion efflux channel involved in maintenance of anion homeostasis. Cl(-) efflux through SLAC1 causes membrane depolarization, which activates outward-rectifying K1 channels, leading to KCl and water efflux to reduce turgor further and cause stomatal closure, that reduces water loss and promotes leaf turgor. Essential for stomatal closure in response to CO(2), abscisic acid (ABA), ozone O(3), light/dark transitions, humidity change, calcium ions, hydrogen peroxide H(2)O(2), reactive oxygen species (ROS), and nitric oxide. Binds to the highly selective inward-rectifying potassium channels KAT1 and AKT2, and inhibits their activities. Functions as an essential negative regulator of inward potassium channels in guard cells. Essential for the efficient stomatal closure and opening in guard cells (PubMed:27002025). Involved in the local and/or systemic stomatal responses (e.g. stomatal closure) to light stress (PubMed:29463779).<ref>PMID:18084014</ref> <ref>PMID:18305482</ref> <ref>PMID:18305484</ref> <ref>PMID:19955405</ref> <ref>PMID:19955427</ref> <ref>PMID:20128877</ref> <ref>PMID:20345603</ref> <ref>PMID:27002025</ref> <ref>PMID:29463779</ref> <ref>PMID:18305482</ref> [https://www.uniprot.org/uniprot/A0A059PIQ0_AEQVI A0A059PIQ0_AEQVI] | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Arabidopsis thaliana]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Lee S]] | ||
+ | [[Category: Lee Y]] |
Current revision
AtSLAC1 6D mutant in closed state
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