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8qp9
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM Structure of Pre-B+AMPPNP Complex (core part)== | |
| - | + | <StructureSection load='8qp9' size='340' side='right'caption='[[8qp9]], [[Resolution|resolution]] 4.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8qp9]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QP9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QP9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.1Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IHP:INOSITOL+HEXAKISPHOSPHATE'>IHP</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qp9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qp9 OCA], [https://pdbe.org/8qp9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qp9 RCSB], [https://www.ebi.ac.uk/pdbsum/8qp9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qp9 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SF3A1_HUMAN SF3A1_HUMAN] Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Dybkov O]] | ||
| + | [[Category: Kastner B]] | ||
| + | [[Category: Kumar V]] | ||
| + | [[Category: Ludwig S]] | ||
| + | [[Category: Luehrmann R]] | ||
| + | [[Category: Stark H]] | ||
| + | [[Category: Urlaub H]] | ||
| + | [[Category: Will CL]] | ||
| + | [[Category: Zhang Z]] | ||
| + | [[Category: Zhong J]] | ||
Current revision
Cryo-EM Structure of Pre-B+AMPPNP Complex (core part)
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Categories: Homo sapiens | Large Structures | Dybkov O | Kastner B | Kumar V | Ludwig S | Luehrmann R | Stark H | Urlaub H | Will CL | Zhang Z | Zhong J
