8bk3
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bk3 OCA], [https://pdbe.org/8bk3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bk3 RCSB], [https://www.ebi.ac.uk/pdbsum/8bk3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bk3 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bk3 OCA], [https://pdbe.org/8bk3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bk3 RCSB], [https://www.ebi.ac.uk/pdbsum/8bk3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bk3 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/LDT2_MYCTO LDT2_MYCTO] Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection.<ref>PMID:20305661</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Current revision
Crystal structure of the transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with diepoxide ketone 1
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