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8r4i
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8r4i is ON HOLD until 2025-11-13 Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of human islet amyloid polypeptide (hIAPP)== | |
| - | + | <StructureSection load='8r4i' size='340' side='right'caption='[[8r4i]], [[Resolution|resolution]] 4.01Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8r4i]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8R4I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8R4I FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.01Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8r4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8r4i OCA], [https://pdbe.org/8r4i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8r4i RCSB], [https://www.ebi.ac.uk/pdbsum/8r4i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8r4i ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IAPP_HUMAN IAPP_HUMAN] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Maj M]] | ||
| + | [[Category: Ooi SA]] | ||
| + | [[Category: Valli D]] | ||
Current revision
Cryo-EM structure of human islet amyloid polypeptide (hIAPP)
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Categories: Homo sapiens | Large Structures | Maj M | Ooi SA | Valli D
