7x14
From Proteopedia
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== Function == | == Function == | ||
| - | [https://www.uniprot.org/uniprot/VAPB_MOUSE VAPB_MOUSE] Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.[UniProtKB:O95292] | + | [https://www.uniprot.org/uniprot/VAPB_MOUSE VAPB_MOUSE] Endoplasmic reticulum (ER)-anchored protein that mediates the formation of contact sites between the ER and endosomes via interaction with FFAT motif-containing proteins such as STARD3 or WDR44. Interacts with STARD3 in a FFAT motif phosphorylation dependent manner. Via interaction with WDR44 participates in neosynthesized protein export. Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.[UniProtKB:O95292] |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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<div class="pdbe-citations 7x14" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 7x14" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[Vesicle-associated membrane protein 3D structures|Vesicle-associated membrane protein 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Current revision
Crystal structure of phospho-FFAT motif of MIGA2 bound to VAPB
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