8qzq
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Single particle cryo-EM co-structure of E. coli AcrB with bound BDM91531 inhibitor== | |
| - | + | <StructureSection load='8qzq' size='340' side='right'caption='[[8qzq]], [[Resolution|resolution]] 3.23Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8qzq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QZQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QZQ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.23Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=WR6:[(2~{R})-1-[[(2~{R})-2,3-bis(oxidanyl)propoxy]-oxidanyl-phosphoryl]oxy-3-undecanoyloxy-propan-2-yl]+tricosanoate'>WR6</scene>, <scene name='pdbligand=XE9:[3-(3-chloranyl-2-piperazin-1-yl-quinolin-6-yl)phenyl]methanamine'>XE9</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qzq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qzq OCA], [https://pdbe.org/8qzq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qzq RCSB], [https://www.ebi.ac.uk/pdbsum/8qzq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qzq ProSAT]</span></td></tr> |
| - | [[Category: Boernsen | + | </table> |
| - | [[Category: Frangakis | + | == Function == |
| - | [[Category: Pos | + | [https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Boernsen C]] | ||
| + | [[Category: Frangakis AS]] | ||
| + | [[Category: Mueller RT]] | ||
| + | [[Category: Pos KM]] | ||
Current revision
Single particle cryo-EM co-structure of E. coli AcrB with bound BDM91531 inhibitor
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