8r66

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Current revision (11:05, 16 April 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8r66 is ON HOLD until Paper Publication
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==Crystal structure of ThsA Macro domain in complex with signaling molecule==
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<StructureSection load='8r66' size='340' side='right'caption='[[8r66]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
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Authors: Tamulaitiene, G., Sabonis, D.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8r66]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_amyloliquefaciens Bacillus amyloliquefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8R66 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8R66 FirstGlance]. <br>
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Description: Crystal structure of ThsA Macro domain in complex with signaling molecule
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.23&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=Y65:(2~{S})-3-[1-[(2~{R},3~{R},4~{S},5~{R})-5-[[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]imidazol-4-yl]-2-azanyl-propanoic+acid'>Y65</scene></td></tr>
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[[Category: Sabonis, D]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8r66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8r66 OCA], [https://pdbe.org/8r66 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8r66 RCSB], [https://www.ebi.ac.uk/pdbsum/8r66 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8r66 ProSAT]</span></td></tr>
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[[Category: Tamulaitiene, G]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/THSA_BACAY THSA_BACAY] Probable membrane protein component of the Thoeris antiviral defense system, composed of ThsA and ThsB. Expression of ThsA and ThsB in B.subtilis (strain BEST7003) confers resistance to phages SBSphiC, SBSphiJ and SPO1 (PubMed:29371424). Activation by a signal generated by ThsB leads to phage resistance (By similarity).[UniProtKB:J8G6Z1]<ref>PMID:29371424</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Bacillus amyloliquefaciens]]
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[[Category: Large Structures]]
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[[Category: Sabonis D]]
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[[Category: Tamulaitiene G]]

Current revision

Crystal structure of ThsA Macro domain in complex with signaling molecule

PDB ID 8r66

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