8t0s

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Current revision (05:19, 5 June 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8t0s is ON HOLD until 2025-06-01
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==Crystal structure of UBE2G2 adduct with phenethyl isothiocyanate (PEITC) at the Cys48 position==
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<StructureSection load='8t0s' size='340' side='right'caption='[[8t0s]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8t0s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8T0S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8T0S FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6M6:S-[(2-PHENYLETHYL)CARBAMOTHIOYL]-L-CYSTEINE'>6M6</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8t0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8t0s OCA], [https://pdbe.org/8t0s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8t0s RCSB], [https://www.ebi.ac.uk/pdbsum/8t0s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8t0s ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/UB2G2_HUMAN UB2G2_HUMAN] Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD).<ref>PMID:20061386</ref> <ref>PMID:22607976</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Ji X]]
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[[Category: Shaw GX]]
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[[Category: Shi G]]
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[[Category: Wang C]]

Current revision

Crystal structure of UBE2G2 adduct with phenethyl isothiocyanate (PEITC) at the Cys48 position

PDB ID 8t0s

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