1oxz
From Proteopedia
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- | [[Image:1oxz.jpg|left|200px]] | ||
- | + | ==Crystal Structure of the Human GGA1 GAT domain== | |
- | + | <StructureSection load='1oxz' size='340' side='right'caption='[[1oxz]], [[Resolution|resolution]] 2.80Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1oxz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OXZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OXZ FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oxz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oxz OCA], [https://pdbe.org/1oxz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oxz RCSB], [https://www.ebi.ac.uk/pdbsum/1oxz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oxz ProSAT]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/GGA1_HUMAN GGA1_HUMAN] Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.<ref>PMID:11301005</ref> | |
- | + | == Evolutionary Conservation == | |
- | + | [[Image:Consurf_key_small.gif|200px|right]] | |
- | == | + | Check<jmol> |
- | + | <jmolCheckbox> | |
- | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ox/1oxz_consurf.spt"</scriptWhenChecked> | |
- | == | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
- | + | <text>to colour the structure by Evolutionary Conservation</text> | |
- | + | </jmolCheckbox> | |
- | == | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oxz ConSurf]. |
- | + | <div style="clear:both"></div> | |
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: He | + | [[Category: He X]] |
- | [[Category: Joachimiak | + | [[Category: Joachimiak A]] |
- | [[Category: Tang | + | [[Category: Tang J]] |
- | [[Category: Terzyan | + | [[Category: Terzyan S]] |
- | [[Category: Zhai | + | [[Category: Zhai P]] |
- | [[Category: Zhang | + | [[Category: Zhang R]] |
- | [[Category: Zhang | + | [[Category: Zhang XC]] |
- | [[Category: Zhu | + | [[Category: Zhu G]] |
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- | + | ||
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Current revision
Crystal Structure of the Human GGA1 GAT domain
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Categories: Homo sapiens | Large Structures | He X | Joachimiak A | Tang J | Terzyan S | Zhai P | Zhang R | Zhang XC | Zhu G