8rhn
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the 55LCC ATPase complex== | |
| - | + | <StructureSection load='8rhn' size='340' side='right'caption='[[8rhn]], [[Resolution|resolution]] 4.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8rhn]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RHN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RHN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.5Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8rhn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rhn OCA], [https://pdbe.org/8rhn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rhn RCSB], [https://www.ebi.ac.uk/pdbsum/8rhn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rhn ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/AFG2A_HUMAN AFG2A_HUMAN] Microcephaly-intellectual disability-sensorineural hearing loss-epilepsy-abnormal muscle tone syndrome. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AFG2A_HUMAN AFG2A_HUMAN] ATP-dependent chaperone, which plays an essential role in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles (PubMed:35354024). Acts together with AFG2B, AIRIM and CINP (PubMed:35354024). May be involved in morphological and functional mitochondrial transformations during spermatogenesis (By similarity).[UniProtKB:Q3UMC0]<ref>PMID:35354024</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Degtjarik O]] | ||
| + | [[Category: Foglizzo M]] | ||
| + | [[Category: Zeqiraj E]] | ||
Current revision
Structure of the 55LCC ATPase complex
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