8riy
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Human NUDT5 with ibrutinib derivative== | |
| - | + | <StructureSection load='8riy' size='340' side='right'caption='[[8riy]], [[Resolution|resolution]] 2.29Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8riy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RIY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RIY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.288Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=W0O:1-(1-methylpiperidin-4-yl)-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine'>W0O</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8riy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8riy OCA], [https://pdbe.org/8riy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8riy RCSB], [https://www.ebi.ac.uk/pdbsum/8riy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8riy ProSAT]</span></td></tr> |
| - | [[Category: Balikci-Akil | + | </table> |
| - | [[Category: Huber | + | == Function == |
| + | [https://www.uniprot.org/uniprot/NUDT5_HUMAN NUDT5_HUMAN] Hydrolyzes with similar activities ADP-ribose ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity.<ref>PMID:17052728</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Balikci-Akil E]] | ||
| + | [[Category: Elkins JM]] | ||
| + | [[Category: Huber KVM]] | ||
Current revision
Human NUDT5 with ibrutinib derivative
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