1pcl

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[[Image:1pcl.gif|left|200px]]
 
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==UNUSUAL STRUCTURAL FEATURES IN THE PARALLEL BETA-HELIX IN PECTATE LYASES==
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The line below this paragraph, containing "STRUCTURE_1pcl", creates the "Structure Box" on the page.
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<StructureSection load='1pcl' size='340' side='right'caption='[[1pcl]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1pcl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dickeya_chrysanthemi Dickeya chrysanthemi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PCL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PCL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pcl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pcl OCA], [https://pdbe.org/1pcl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pcl RCSB], [https://www.ebi.ac.uk/pdbsum/1pcl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pcl ProSAT]</span></td></tr>
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{{STRUCTURE_1pcl| PDB=1pcl | SCENE= }}
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</table>
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== Function ==
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'''UNUSUAL STRUCTURAL FEATURES IN THE PARALLEL BETA-HELIX IN PECTATE LYASES'''
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[https://www.uniprot.org/uniprot/PLYE1_DICCH PLYE1_DICCH] Involved in maceration and soft-rotting of plant tissue.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==Overview==
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Check<jmol>
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BACKGROUND: A new type of domain structure, an all parallel beta class, has recently been observed in two pectate lyases, PelC and PelE. The atomic models have been analyzed to determine whether the new tertiary fold exhibits unusual structural features. RESULTS: The polypeptide backbone exhibits no new types of secondary structural elements. However, novel features occur in the amino acid side chain interactions. The side chain atoms form linear stacks that include asparagine ladders, serine stacks, aliphatic stacks, and ringed-residue stacks. A new type of beta-sandwich between parallel beta-sheets is observed with properties that are more characteristic of antiparallel beta-sheets. CONCLUSION: An analysis of the PelC and PelE structures, belonging to an all parallel beta structural class, reveals novel amino acid side chain interactions, a new type of beta-sandwich and an atypical amino acid composition of parallel beta-sheets. The findings are relevant to three-dimensional structural predictions.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pc/1pcl_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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1PCL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Erwinia_chrysanthemi Erwinia chrysanthemi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PCL OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==Reference==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pcl ConSurf].
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Unusual structural features in the parallel beta-helix in pectate lyases., Yoder MD, Lietzke SE, Jurnak F, Structure. 1993 Dec 15;1(4):241-51. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8081738 8081738]
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<div style="clear:both"></div>
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[[Category: Erwinia chrysanthemi]]
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__TOC__
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[[Category: Pectate lyase]]
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</StructureSection>
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[[Category: Single protein]]
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[[Category: Dickeya chrysanthemi]]
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[[Category: Jurnak, F.]]
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[[Category: Large Structures]]
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[[Category: Keen, N T.]]
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[[Category: Jurnak F]]
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[[Category: Lietzke, S E.]]
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[[Category: Keen NT]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:56:25 2008''
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[[Category: Lietzke SE]]

Current revision

UNUSUAL STRUCTURAL FEATURES IN THE PARALLEL BETA-HELIX IN PECTATE LYASES

PDB ID 1pcl

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