8xu5
From Proteopedia
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(New page: '''Unreleased structure''' The entry 8xu5 is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The Crystal Structure of RORgT from Biortus.== |
| - | + | <StructureSection load='8xu5' size='340' side='right'caption='[[8xu5]], [[Resolution|resolution]] 3.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8xu5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XU5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XU5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xu5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xu5 OCA], [https://pdbe.org/8xu5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xu5 RCSB], [https://www.ebi.ac.uk/pdbsum/8xu5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xu5 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RORG_HUMAN RORG_HUMAN] Possible nuclear receptor for hydroxycholesterols, the binding of which strongly promotes coactivators recruitment. Essential for thymopoiesis and the development of several secondary lymphoid tissues, including lymph nodes. Involved in lineage specification of uncommitted CD4(+) T-helper cells into Th17 cells. Regulate the expression of several components of the circadian clock. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Cheng W]] | ||
| + | [[Category: Qi J]] | ||
| + | [[Category: Wang F]] | ||
| + | [[Category: Wu B]] | ||
| + | [[Category: Yuan Z]] | ||
Current revision
The Crystal Structure of RORgT from Biortus.
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Categories: Homo sapiens | Large Structures | Cheng W | Qi J | Wang F | Wu B | Yuan Z
