8rsr
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of marine actinobacteria clade rhodopsin (MAR) - human GTPase Arf1 (L8K,Q71L) chimera; N state== | |
| - | + | <StructureSection load='8rsr' size='340' side='right'caption='[[8rsr]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8rsr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Unclassified_Actinomycetia Unclassified Actinomycetia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RSR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RSR FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=LFA:EICOSANE'>LFA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8rsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rsr OCA], [https://pdbe.org/8rsr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rsr RCSB], [https://www.ebi.ac.uk/pdbsum/8rsr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rsr ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ARF1_HUMAN ARF1_HUMAN] GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Unclassified Actinomycetia]] | ||
| + | [[Category: Astashkin R]] | ||
| + | [[Category: Bratanov D]] | ||
| + | [[Category: Bukhdruker S]] | ||
| + | [[Category: Gordeliy V]] | ||
| + | [[Category: Kovalev K]] | ||
Current revision
Crystal structure of marine actinobacteria clade rhodopsin (MAR) - human GTPase Arf1 (L8K,Q71L) chimera; N state
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