8c8h

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Current revision (07:06, 21 November 2024) (edit) (undo)
 
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== Function ==
== Function ==
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[https://www.uniprot.org/uniprot/RP22_VACCW RP22_VACCW] Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates (PubMed:31835031). Responsible for the transcription of early, intermediate and late genes. DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of OPG118 and OPG133, thereby allowing the early genes transcription. Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.<ref>PMID:19759131</ref> <ref>PMID:31835031</ref>
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[https://www.uniprot.org/uniprot/RP132_VACCW RP132_VACCW] Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes. DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of OPG118 and OPG133, thereby allowing the early genes transcription. Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.<ref>PMID:31835031</ref>
== References ==
== References ==
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Current revision

Cryo EM structure of the vaccinia complete RNA polymerase complex lacking the capping enzyme

PDB ID 8c8h

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