1pu1
From Proteopedia
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| - | [[Image:1pu1.gif|left|200px]] | ||
| - | + | ==Solution structure of the Hypothetical protein mth677 from Methanothermobacter Thermautotrophicus== | |
| - | + | <StructureSection load='1pu1' size='340' side='right'caption='[[1pu1]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1pu1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PU1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PU1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pu1 OCA], [https://pdbe.org/1pu1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pu1 RCSB], [https://www.ebi.ac.uk/pdbsum/1pu1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pu1 ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | '' | + | [https://www.uniprot.org/uniprot/Y677_METTH Y677_METTH] |
| - | + | <div style="background-color:#fffaf0;"> | |
| - | + | == Publication Abstract from PubMed == | |
| - | == | + | |
The structure of Mth677, a hypothetical protein from Methanobacterium thermoautotrophicum (Mth), has been determined by using heteronuclear nuclear magnetic resonance (NMR) methods on a double-labeled (15)N-(13)C sample. Mth677 adopts a novel alpha+beta fold, consisting of two alpha-helices (one N terminal and one C terminal) packed on the same side of a central beta-hairpin. This structure is likely shared by its three orthologs, detected in three other Archaebacteria. There are no clear features in the sequences of these proteins or in the genome organization of Mth to make a reliable functional assignment to this protein. However, the structural similarity to Escherichia coli MinE, the protein which controls that division occurs at the midcell site, lends support to the proposal that Mth677 might be, in Mth, the counterpart of the topological specificity domain of MinE in E. coli. | The structure of Mth677, a hypothetical protein from Methanobacterium thermoautotrophicum (Mth), has been determined by using heteronuclear nuclear magnetic resonance (NMR) methods on a double-labeled (15)N-(13)C sample. Mth677 adopts a novel alpha+beta fold, consisting of two alpha-helices (one N terminal and one C terminal) packed on the same side of a central beta-hairpin. This structure is likely shared by its three orthologs, detected in three other Archaebacteria. There are no clear features in the sequences of these proteins or in the genome organization of Mth to make a reliable functional assignment to this protein. However, the structural similarity to Escherichia coli MinE, the protein which controls that division occurs at the midcell site, lends support to the proposal that Mth677 might be, in Mth, the counterpart of the topological specificity domain of MinE in E. coli. | ||
| - | + | Solution structure of the hypothetical protein Mth677 from Methanobacterium thermoautotrophicum: a novel alpha+beta fold.,Blanco FJ, Yee A, Campos-Olivas R, Ortiz AR, Devos D, Valencia A, Arrowsmith CH, Rico M Protein Sci. 2004 Jun;13(6):1458-65. PMID:15152082<ref>PMID:15152082</ref> | |
| - | + | ||
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| + | <div class="pdbe-citations 1pu1" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Methanothermobacter thermautotrophicus]] | [[Category: Methanothermobacter thermautotrophicus]] | ||
| - | + | [[Category: Arrowsmith CH]] | |
| - | [[Category: Arrowsmith | + | [[Category: Blanco FJ]] |
| - | [[Category: Blanco | + | [[Category: Campos-Olivas R]] |
| - | [[Category: Campos-Olivas | + | [[Category: Devos D]] |
| - | [[Category: Devos | + | [[Category: Rico M]] |
| - | [[Category: Rico | + | [[Category: Valencia A]] |
| - | [[Category: Valencia | + | [[Category: Yee A]] |
| - | [[Category: Yee | + | |
| - | + | ||
| - | + | ||
Current revision
Solution structure of the Hypothetical protein mth677 from Methanothermobacter Thermautotrophicus
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