7bkg
From Proteopedia
(Difference between revisions)
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<StructureSection load='7bkg' size='340' side='right'caption='[[7bkg]], [[Resolution|resolution]] 2.33Å' scene=''> | <StructureSection load='7bkg' size='340' side='right'caption='[[7bkg]], [[Resolution|resolution]] 2.33Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'> | + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BKG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BKG FirstGlance]. <br> |
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.326Å</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.326Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=U0Z:5,6-dihydro-2-imino-2H,4H-thiazolo(5,4,3-IJ)quinoline'>U0Z</scene></td></tr> | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=U0Z:5,6-dihydro-2-imino-2H,4H-thiazolo(5,4,3-IJ)quinoline'>U0Z</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bkg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bkg OCA], [https://pdbe.org/7bkg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bkg RCSB], [https://www.ebi.ac.uk/pdbsum/7bkg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bkg ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bkg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bkg OCA], [https://pdbe.org/7bkg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bkg RCSB], [https://www.ebi.ac.uk/pdbsum/7bkg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bkg ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/NNMT_HUMAN NNMT_HUMAN] Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Liesum A]] | [[Category: Liesum A]] | ||
[[Category: Schreuder HA]] | [[Category: Schreuder HA]] | ||
Current revision
Co-crystal structure of Human Nicotinamide N-methyltransferase (NNMT) with the tricyclic inhibitor (2)
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